Evidence map›Paper›PMID 34073140›Full record

ArticleInternational journal of molecular sciences2021

Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca

Egor A Turovsky, Maria V Turovskaya, Evgeniya I Fedotova, Alexey A Babaev, Viktor S Tarabykin, Elena G Varlamova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Egor A TurovskyFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences," Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-2528-8798
Maria V TurovskayaFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences," Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Evgeniya I FedotovaFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences," Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Alexey A BabaevInstitute of Neuroscience, Lobachevsky State University of Nizhniy Novgorod, 23 Prospekt Gagarina, 603950 Nizhny Novgorod, Russia.
Viktor S TarabykinInstitute of Neuroscience, Lobachevsky State University of Nizhniy Novgorod, 23 Prospekt Gagarina, 603950 Nizhny Novgorod, Russia.
Elena G VarlamovaFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences," Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Institute of Cell Biophysics · RUCharité - Universitätsmedizin Berlin · DEN. I. Lobachevsky State University of Nizhny Novgorod · RU

Funding

Competitiveness Program of Lobachevsky State University of Nizhni Novgorod Н-413-99_2020-2021Grants from the President of the Russian Federation MK-677.2019.4
6 · The paper itself

Abstract

Transcription factors Satb1 and Satb2 are involved in the processes of cortex development and maturation of neurons. Alterations in the expression of their target genes can lead to neurodegenerative processes. Molecular and cellular mechanisms of regulation of neurotransmission by these transcription factors remain poorly understood. In this study, we have shown that transcription factors Satb1 and Satb2 participate in the regulation of genes encoding the NMDA-, AMPA-, and KA- receptor subunits and the inhibitory GABA(A) receptor. Deletion of gene for either Satb1 or Satb2 homologous factors induces the expression of genes encoding the NMDA receptor subunits, thereby leading to higher amplitudes of Ca

Indexed as

Calcium SignalingNeurogliaSynaptic TransmissionAnimalsCells, CulturedFemaleMaleMatrix Attachment Region Binding ProteinsMiceMice, KnockoutReceptors, GABAReceptors, GlutamateTranscription FactorsMatrix Attachment Region Binding ProteinsReceptors, GABAReceptors, GlutamateSatb1 protein, mouseSATB2 protein, mouseTranscription FactorscalciumcortexGABA-receptorsgene deletionglutamate receptorsneuronsSatb1Satb2signal transduction

Identifiers

PMID34073140
PMCPMC8198236
OpenAlexW3164136812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.