Evidence map›Paper›PMID 34073041›Full record

ArticleInternational journal of molecular sciences2021

An Engineered

Alon M Douek, Mitra Amiri Khabooshan, Jason Henry, Sebastian-Alexander Stamatis, Florian Kreuder, Georg Ramm, Minna-Liisa Änkö, Donald Wlodkowic, Jan Kaslin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Genome Editing Tools for Lysosomal Storage Disorders.Advances in experimental medicine and biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alon M DouekAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC 3800, Australia.ORCID 0000-0001-5739-3835
Mitra Amiri KhabooshanAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC 3800, Australia.
Jason HenryNeurotoxicology Lab, School of Science (Biosciences), RMIT University, Bundoora, VIC 3083, Australia.ORCID 0000-0002-0059-3868
Sebastian-Alexander StamatisAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC 3800, Australia.
Florian KreuderAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC 3800, Australia.
Georg RammRamaciotti Centre for Cryo-Electron Microscopy, Monash University, Clayton, VIC 3800, Australia.
Minna-Liisa ÄnköCentre for Reproductive Health and Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.ORCID 0000-0003-0446-3566
Donald WlodkowicNeurotoxicology Lab, School of Science (Biosciences), RMIT University, Bundoora, VIC 3083, Australia.ORCID 0000-0002-0780-3362
Jan KaslinAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC 3800, Australia.
Australian Regenerative Medicine Institute · AURMIT University · AUHudson Institute of Medical Research · AU

Funding

National Health and Medical Research Council GNT1068411
6 · The paper itself

Abstract

Mucopolysaccharidosis IIIA (MPS IIIA, Sanfilippo syndrome type A), a paediatric neurological lysosomal storage disease, is caused by impaired function of the enzyme

Indexed as

Disease Models, AnimalMucopolysaccharidosis IIIAnimalsHumansHydrolasesMutationPhenotypeZebrafishHydrolasesN-sulfoglucosamine sulfohydrolaseanimal disease modelchildhood dementiaCRISPR/Cas9heparan sulfatelysosomal storage disordermucopolysaccharidosisneuroinflammationSanfilippo syndromezebrafish

Identifiers

PMID34073041
PMCPMC8197930
OpenAlexW3165868538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.