Evidence map›Paper›PMID 34073006›Full record

ArticleInternational journal of molecular sciences2021

A Screening of the MMV Pandemic Response Box Reveals Epetraborole as a New Potent Inhibitor against

Taeho Kim, Bui-Thi-Bich Hanh, Boeun Heo, Nguyenthanh Quang, Yujin Park, Jihyeon Shin, Seunghyeon Jeon, June-Woo Park, Kirandeep Samby, Jichan Jang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Antimicrobial potential of compounds from the MMV pandemic response box and COVID box against carbapenem-resistant Acinetobacter baumannii.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. Genome-wide Screening of the Escherichia coli Keio Knockout Collection Identifies Genetic Determinants of Epetraborole Hypersusceptibility.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  4. Identification of a Drug Candidate againstJournal of microbiology and biotechnology · 2025
    Article
  5. Article
  6. Oral oxaborole MRX-5 exhibits efficacy against pulmonaryAntimicrobial agents and chemotherapy · 2024
    Article
  7. Efficacy of epetraborole againstAntimicrobial agents and chemotherapy · 2024
    Article
  8. Article
  9. Article
  10. Antimicrobial and Antibiofilm Effects of Bithionol againstAntibiotics (Basel, Switzerland) · 2024
    Article
  11. Review
  12. Article
  13. Exploring antibiotic resistance mechanisms inFrontiers in microbiology · 2024
    Review
  14. Article
  15. Design, Synthesis and Antimicrobial Evaluation of NewInternational journal of molecular sciences · 2023
    Article
  16. Article
  17. Article
  18. Cellular and Molecular Mechanisms in Mycobacterial Infection.International journal of molecular sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Taeho KimDivision of Applied Life Science (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Bui-Thi-Bich HanhDivision of Applied Life Science (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Boeun HeoMolecular Mechanisms of Antibiotics, Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Nguyenthanh QuangMolecular Mechanisms of Antibiotics, Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Yujin ParkMolecular Mechanisms of Antibiotics, Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Jihyeon ShinMolecular Mechanisms of Antibiotics, Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Seunghyeon JeonDivision of Life Science, Gyeongsang National University, Jinju 52828, Korea.
June-Woo ParkDepartment of Environmental Toxicology and Chemistry, Korea Institute of Toxicology, Jinju 52843, Korea.
Kirandeep SambyMedicines for Malaria Venture (MMV), 20, Route de Pré-Bois, 1215 Geneva, Switzerland.
Jichan JangMolecular Mechanisms of Antibiotics, Division of Life Science, Department of Bio & Medical Big Data (BK21 Four Program), Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Gyeongsang National University · KRKorea University of Science and Technology · KRMedicines for Malaria Venture · CH

Funding

National Research Foundation of Korea 2020R1A2C1004077
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsBoron CompoundsDrug Evaluation, PreclinicalDrug RepositioningMycobacterium abscessusMycobacterium Infections, NontuberculousZebrafish3-(aminomethyl)-7-(3-hydroxypropoxy)-1-hydroxy-1,3-dihydro-2,1-benzoxaboroleAnti-Bacterial AgentsBoron Compoundsantibioticsbenzoxaborolesdrug discoveryepetraboroleMycobacterium abscessus

Identifiers

PMID34073006
PMCPMC8199016
OpenAlexW3165333000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.