ArticlePolymers2021
An In-Vitro Evaluation of the Characteristics of Zein-Based Films for the Release of Lactobionic Acid and the Effects of Oleic Acid.
Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Interfacial Interactions and Structural Evolution of Gelatin/Zein Nanofiber Composites Modulated by Poly(Vinyl Alcohol).Foods (Basel, Switzerland) · 2026Article
- Zein-based polysaccharide-tannic acid films as multifunctional barriers to prevent post-surgical adhesions.International journal of pharmaceutics: X · 2026Article
- From acidification to multi-targeted cellular modulation: dual impact of hydroxy acids on the skin microbiota and the epidermal barrier.Frontiers in cellular and infection microbiology · 2026Review
- Lactobionic Acid as a Biocompatibility Switch: Physicochemical and Biological Characterization of Copper(II)-Primaquine Complexes.Bioinorganic chemistry and applications · 2026Article
- Electrospun nanofibers incorporating lactobionic acid as novel active packaging materials: biological activities and toxicological evaluation.Discover nano · 2024Article
- Multi-Enzymatic Synthesis of Lactobionic Acid Using Wood-Degrading Enzymes Produced by White Rot Fungi.Metabolites · 2023Article
- Biomaterials in Medical Applications.Polymers · 2023Article
- Effects of Surfactants on Zein Cast Films for Simultaneous Delivery of Two Hydrophilic Active Components.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactobionic acid (LBA) is widely used in different industrial sectors owing to its biocompatibility characteristics as well as antioxidant and antimicrobial properties. In this study, mixtures of the protein zein with LBA and with the addition of oleic acid (OA) as a ternary system were investigated as drug delivery films for the release of LBA. The chosen combinations exploit the vast difference in water solubility between LBA and the other two components (zein and OA). DSC thermograms and dynamic mechanical spectra, alongside electron microscopy images, were used to describe the microstructural features of the films and were found to provide insights for the release of LBA from the two examined zein-based films immersed in an aqueous physiological solution. For both film systems, a burst release behavior was observed, followed by a rapid and total extraction of LBA. The required immersion time for the total extraction of LBA was greatly reduced when oleic acid was added to the precursor solution mixture for producing the films. The LBA released from the zein-based films was found to exhibit both the expected antioxidant properties as well as exerting bacteriostatic effects towards
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