Evidence map›Paper›PMID 34072924›Full record

ArticleInternational journal of environmental research and public health2021

Adverse Health Effects in Women Farmers Indirectly Exposed to Pesticides.

Jose Martin-Reina, Alfredo G Casanova, Bouchra Dahiri, Isaías Fernández, Ana Fernández-Palacín, Juan Bautista, Ana I Morales, Isabel Moreno

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Impact of Pesticide Exposure among Rural and Urban Female Population. An Overview.International journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jose Martin-ReinaDepartment of Nutrition, Food Chemistry and Toxicology, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain.
Alfredo G CasanovaToxicology Unit, Department of Physiology and Pharmacology, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca (USAL), 37007 Salamanca, Spain.ORCID 0000-0002-0725-6637
Bouchra DahiriDepartment of Nutrition, Food Chemistry and Toxicology, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain.ORCID 0000-0002-7740-1051
Isaías FernándezEstepa Clinical Management Unit, Andalusian Health Service, C/Médico Antonio Vilches s/n, 41560 Sevilla, Spain.
Ana Fernández-PalacínArea of Preventive Medicine and Public Health, Facultad de Medicina, Avda. Dr. Fedriani, s/n, 41009 Sevilla, Spain.
Juan BautistaDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain.
Ana I MoralesToxicology Unit, Department of Physiology and Pharmacology, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca (USAL), 37007 Salamanca, Spain.ORCID 0000-0001-6836-6138
Isabel MorenoDepartment of Nutrition, Food Chemistry and Toxicology, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain.ORCID 0000-0002-6542-3210
Universidad de Sevilla · ESUniversidad de Salamanca · ESAndalusian Health Service · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Farmers are among the most vulnerable populations because of the exposure to low levels of pesticides. Acetylcholinesterase and butyrylcholinesterase activities are considered as biomarkers of pesticides poisoning. However, biomarkers of oxidative stress are also playing an important role in toxicity of these contaminants. Further, increased activities of gamma-glutamyltransferase, alanine aminotransferase, urea and creatinine have been linked with hepatic and nephrotoxic cell damage, respectively. The aim of this study was to ascertain if the indirect exposure to pesticides leads to some biochemical parameter changes. Thus, cholinesterase activities, oxidative stress status (lipid and protein oxidation), hepatic function (AST and ALT levels), hormonal function (TSH, T4, FSH, LH and AMH), renal function (serum creatinine and urea), as well as possible subclinical kidney damage (urinary proteins and biomarkers of early kidney damage) were evaluated in farmer women who collect fruits and vegetables comparing with a group of women non-occupational exposed to pesticides but living in the same rural environment. Samples were taken periodically along one year to relate the observed effects to a chronic exposure. Our main results showed for the first time a subclinical kidney damage in a rural setting with indirect chronic exposure to pesticides.

Indexed as

Occupational ExposurePesticidesAcetylcholinesteraseAlanine TransaminaseFarmersFemaleHumansAcetylcholinesteraseAlanine TransaminasePesticidescholinesteraseearly kidney damageoxidative stresspesticideswomen farmers

Identifiers

PMID34072924
PMCPMC8198255
OpenAlexW3164817553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.