ArticleViruses2021
Discovery and Characterization of Actively Replicating DNA and Retro-Transcribing Viruses in Lower Vertebrate Hosts Based on RNA Sequencing.
Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Carcass-Based Surveillance of Amphibian Herpesviruses, Ranaviruses andPathogens (Basel, Switzerland) · 2026Article
- A novel amphibian herpesvirus (candidate Batravirus ranidallo5) associated with disease in free-ranging Iberian painted frogs (Discoglossus galganoi) in Spain.Scientific reports · 2025Article
- Identification and characterization of a novel papillomavirus in thornback skate (Microbial genomics · 2025Article
- Metagenomic analysis uncovers novel hepadnaviruses and nackednaviruses.Scientific reports · 2025Article
- A parasite odyssey: An RNA virus concealed inVirus evolution · 2024Article
- Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style.Nature communications · 2023Article
- Virome Analysis of Normal and Growth Retardation Disease-Affected Macrobrachium rosenbergii.Microbiology spectrum · 2022Article
- First Isolation of a Herpesvirus (FamilyAnimals : an open access journal from MDPI · 2022Article
- Revealing the uncharacterised diversity of amphibian and reptile viruses.ISME communications · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a previous study, a metatranscriptomics survey of RNA viruses in several important lower vertebrate host groups revealed huge viral diversity, transforming the understanding of the evolution of vertebrate-associated RNA virus groups. However, the diversity of the DNA and retro-transcribing viruses in these host groups was left uncharacterized. Given that RNA sequencing is capable of revealing viruses undergoing active transcription and replication, we collected previously generated datasets associated with lower vertebrate hosts, and searched them for DNA and retro-transcribing viruses. Our results revealed the complete genome, or "core gene sets", of 18 vertebrate-associated DNA and retro-transcribing viruses in cartilaginous fishes, ray-finned fishes, and amphibians, many of which had high abundance levels, and some of which showed systemic infections in multiple organs, suggesting active transcription or acute infection within the host. Furthermore, these new findings recharacterized the evolutionary history in the families
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.