Evidence map›Paper›PMID 34072867›Full record

ArticleCancers2021

Whole-Lesion Apparent Diffusion Coefficient Histogram Analysis: Significance for Discriminating Lung Cancer from Pulmonary Abscess and Mycobacterial Infection.

Katsuo Usuda, Shun Iwai, Aika Yamagata, Yoshihito Iijima, Nozomu Motono, Munetaka Matoba, Mariko Doai, Keiya Hirata, Hidetaka Uramoto

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Katsuo UsudaDepartment of Thoracic Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.ORCID 0000-0001-6803-9356
Shun IwaiDepartment of Thoracic Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.
Aika YamagataDepartment of Thoracic Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.
Yoshihito IijimaDepartment of Thoracic Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.
Nozomu MotonoDepartment of Thoracic Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.
Munetaka MatobaDepartment of Radiology, Kanazawa Medical University, Ishikawa 920-0293, Japan.
Mariko DoaiDepartment of Radiology, Kanazawa Medical University, Ishikawa 920-0293, Japan.
Keiya HirataMRI Center, Kanazawa Medical University Hospital, Ishikawa 920-0293, Japan.
Hidetaka UramotoDepartment of Thoracic Surgery, Kanazawa Medical University, Ishikawa 920-0293, Japan.ORCID 0000-0003-4451-4225
Kanazawa Medical University · JPKanazawa Medical University Hospital · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology, Japan 20K09172
6 · The paper itself

Abstract

Diffusion-weighted magnetic resonance imaging (DWI) can differentiate malignant from benign pulmonary nodules. However, it is difficult to differentiate pulmonary abscesses and mycobacterial infections (PAMIs) from lung cancers because PAMIs show restricted diffusion in DWI. The study purpose is to establish the role of ADC histogram for differentiating lung cancer from PAMI. There were 41 lung cancers (25 adenocarcinomas, 16 squamous cell carcinomas), and 19 PAMIs (9 pulmonary abscesses, 10 mycobacterial infections). Parameters more than 60% of the area under the ROC curve (AUC) were ADC, maximal ADC, mean ADC, median ADC, most frequency ADC, kurtosis of ADC, and volume of lesion. There were significant differences between lung cancer and PAMI in ADC, mean ADC, median ADC, and most frequency ADC. The ADC (1.19 ± 0.29 × 10

Indexed as

ADC histogramapparent diffusion coefficient (ADC)diffusion-weighted magnetic resonance imaging (DWI)lung cancermagnetic resonance imaging (MRI)pulmonary abscess and mycobacterial infection (PAMI)

Identifiers

PMID34072867
PMCPMC8198705
OpenAlexW3165171887

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.