Evidence map›Paper›PMID 34072865›Full record

ArticleCancers2021

Automatized Hepatic Tumor Volume Analysis of Neuroendocrine Liver Metastases by Gd-EOB MRI-A Deep-Learning Model to Support Multidisciplinary Cancer Conference Decision-Making.

Uli Fehrenbach, Siyi Xin, Alexander Hartenstein, Timo Alexander Auer, Franziska Dräger, Konrad Froböse, Henning Jann, Martina Mogl, Holger Amthauer, Dominik Geisel and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Update on the Use of Artificial Intelligence in Hepatobiliary MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Uli FehrenbachDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.ORCID 0000-0003-3622-3268
Siyi XinDivision of Gastroenterology, Medical Department, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Alexander HartensteinDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Timo Alexander AuerDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Franziska DrägerDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Konrad FroböseDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Henning JannDivision of Gastroenterology, Medical Department, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Martina MoglDepartment of Surgery Campus Charité Mitte/Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-3676-047X
Holger AmthauerDepartment of Nuclear Medicine, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.ORCID 0000-0003-4414-0657
Dominik GeiselDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Timm DeneckeDepartment of Diagnostic and Interventional Radiology, University Hospital Leipzig, 04103 Leipzig, Germany.
Bertram WiedenmannDivision of Gastroenterology, Medical Department, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Tobias PenzkoferDepartment of Radiology, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.ORCID 0000-0001-9591-8575
Charité - Universitätsmedizin Berlin · DEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEBayer (Germany) · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid quantification of liver metastasis for diagnosis and follow-up is an unmet medical need in patients with secondary liver malignancies. We present a 3D-quantification model of neuroendocrine liver metastases (NELM) using gadoxetic-acid (Gd-EOB)-enhanced MRI as a useful tool for multidisciplinary cancer conferences (MCC).

methodsManual 3D-segmentations of NELM and livers (149 patients in 278 Gd-EOB MRI scans) were used to train a neural network (

resultsInternal validation of the model's accuracy showed a high overlap for NELM and livers (Matthew's correlation coefficient (φ): 0.76/0.95, respectively) with higher φ in larger NELM volume (φ = 0.80 vs. 0.71;

conclusionThe model shows high accuracy in 3D-quantification of NELM and HTL in Gd-EOB-MRI. The model's measurements correlated well with MCC's evaluation of therapeutic response.

Indexed as

automatized quantificationdeep learningliver metastasesMRImultidisciplinary cancer conferenceneuroendocrine neoplasms

Identifiers

PMID34072865
PMCPMC8199286
OpenAlexW3164763978

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.