Evidence map›Paper›PMID 34072804›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Application and Performance of Artificial Intelligence Technology in Oral Cancer Diagnosis and Prediction of Prognosis: A Systematic Review.

Sanjeev B Khanagar, Sachin Naik, Abdulaziz Abdullah Al Kheraif, Satish Vishwanathaiah, Prabhadevi C Maganur, Yaser Alhazmi, Shazia Mushtaq, Sachin C Sarode, Gargi S Sarode, Alessio Zanza and 2 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06862414 (Application and Validation of a Smartphone-based Deep Learning System for Oral Potentially Malignant Disorders), which is not on this map. Cited by 41 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06862414 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Application and Validation of a Smartphone-based Deep Learning System for Oral Potentially Malignant Disorders (OPMD) and Oral Cancer Screening

TypeinterventionalSponsorNational Taiwan University HospitalRan2025 to 2025Enrolled954ConditionsCancer Screening, Oral Cancer, Oral Potentially Malignant DisordersArmsSmartphone-based deep learning system
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sanjeev B KhanagarPreventive Dental Science Department, College of Dentistry, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11481, Saudi Arabia.ORCID 0000-0002-4098-7773
Sachin NaikDental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.
Abdulaziz Abdullah Al KheraifDental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.
Satish VishwanathaiahDepartment of Preventive Dental Sciences, Division of Pedodontics, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-8376-297X
Prabhadevi C MaganurDepartment of Preventive Dental Sciences, Division of Pedodontics, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-0959-2597
Yaser AlhazmiDepartment of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.
Shazia MushtaqCollege of Applied Medical Sciences, Dental Health Department, King Saud University, Riyadh 12372, Saudi Arabia.
Sachin C SarodeDepartment of Oral and Maxillofacial Pathology, Dr. D.Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune 411018, India.ORCID 0000-0003-1856-0957
Gargi S SarodeDepartment of Oral and Maxillofacial Pathology, Dr. D.Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune 411018, India.
Alessio ZanzaDepartment of Maxillo and Oro-Facial Sciences, University of Rome La Sapienza, 00185 Rome, Italy.ORCID 0000-0002-2062-8140
Luca TestarelliDepartment of Maxillo and Oro-Facial Sciences, University of Rome La Sapienza, 00185 Rome, Italy.ORCID 0000-0003-3904-3000
Shankargouda PatilDepartment of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0001-7246-5497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer (OC) is a deadly disease with a high mortality and complex etiology. Artificial intelligence (AI) is one of the outstanding innovations in technology used in dental science. This paper intends to report on the application and performance of AI in diagnosis and predicting the occurrence of OC. In this study, we carried out data search through an electronic search in several renowned databases, which mainly included PubMed, Google Scholar, Scopus, Embase, Cochrane, Web of Science, and the Saudi Digital Library for articles that were published between January 2000 to March 2021. We included 16 articles that met the eligibility criteria and were critically analyzed using QUADAS-2. AI can precisely analyze an enormous dataset of images (fluorescent, hyperspectral, cytology, CT images, etc.) to diagnose OC. AI can accurately predict the occurrence of OC, as compared to conventional methods, by analyzing predisposing factors like age, gender, tobacco habits, and bio-markers. The precision and accuracy of AI in diagnosis as well as predicting the occurrence are higher than the current, existing clinical strategies, as well as conventional statistics like cox regression analysis and logistic regression.

Indexed as

artificial intelligenceartificial neural networksmachine learningoral cancer diagnosisoral cancer prediction

Identifiers

PMID34072804
PMCPMC8227647

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.