Evidence map›Paper›PMID 34072803›Full record

ArticleTropical medicine and infectious disease2021

Operational Research to Assess the Real-Time Impact of COVID-19 on TB and HIV Services: The Experience and Response from Health Facilities in Harare, Zimbabwe.

Pruthu Thekkur, Kudakwashe C Takarinda, Collins Timire, Charles Sandy, Tsitsi Apollo, Ajay M V Kumar, Srinath Satyanarayana, Hemant D Shewade, Mohammed Khogali, Rony Zachariah and 3 more

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Lived experiences of tuberculosis patients accessing treatment during COVID-19 in Zimbabwe.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
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  17. COVID-19: Current Challenges and Future Perspectives.Tropical medicine and infectious disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pruthu ThekkurInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0001-5257-5074
Kudakwashe C TakarindaInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0002-2980-7735
Collins TimireInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
Charles SandyAIDS and TB Department, Ministry of Health and Child Care, Causeway, Harare P.O. Box CY 1122, Zimbabwe.
Tsitsi ApolloAIDS and TB Department, Ministry of Health and Child Care, Causeway, Harare P.O. Box CY 1122, Zimbabwe.
Ajay M V KumarInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0003-1011-8531
Srinath SatyanarayanaInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0002-5420-2551
Hemant D ShewadeInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0002-8242-1911
Mohammed KhogaliSpecial Programme for Research and Training in Tropical Disease (TDR), World Health Organization, 1211 Geneva, Switzerland.
Rony ZachariahSpecial Programme for Research and Training in Tropical Disease (TDR), World Health Organization, 1211 Geneva, Switzerland.ORCID 0000-0002-2915-9328
I D RusenVital Strategies, New York, NY 10005, USA.
Selma Dar BergerInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.
Anthony D HarriesInternational Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.ORCID 0000-0001-6113-9741

Funding

Bloomberg Philanthropies through a grant with Vital Strategies and Resolve to Save Lives 78941World Health Organization 001
6 · The paper itself

Abstract

When COVID-19 was declared a pandemic, there was concern that TB and HIV services in Zimbabwe would be severely affected. We set up real-time monthly surveillance of TB and HIV activities in 10 health facilities in Harare to capture trends in TB case detection, TB treatment outcomes and HIV testing and use these data to facilitate corrective action. Aggregate data were collected monthly during the COVID-19 period (March 2020-February 2021) using EpiCollect5 and compared with monthly data extracted for the pre-COVID-19 period (March 2019-February 2020). Monthly reports were sent to program directors. During the COVID-19 period, there was a decrease in persons with presumptive pulmonary TB (40.6%), in patients registered for TB treatment (33.7%) and in individuals tested for HIV (62.8%). The HIV testing decline improved in the second 6 months of the COVID-19 period. However, TB case finding deteriorated further, associated with expiry of diagnostic reagents. During the COVID-19 period, TB treatment success decreased from 80.9 to 69.3%, and referral of HIV-positive persons to antiretroviral therapy decreased from 95.7 to 91.7%. Declining trends in TB and HIV case detection and TB treatment outcomes were not fully redressed despite real-time monthly surveillance. More support is needed to transform this useful information into action.

Indexed as

antiretroviral therapyCOVID-19EpiCollect5HarareHIVoperational researchpresumptive tuberculosisTB treatment outcomestuberculosisZimbabwe

Identifiers

PMID34072803
PMCPMC8261627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.