Evidence map›Paper›PMID 34072718›Full record

SynthesisNutrients2021

Does Branched-Chain Amino Acids (BCAAs) Supplementation Attenuate Muscle Damage Markers and Soreness after Resistance Exercise in Trained Males? A Meta-Analysis of Randomized Controlled Trials.

Chutimon Khemtong, Chia-Hua Kuo, Chih-Yen Chen, Salvador J Jaime, Giancarlo Condello

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Effect ofNutrients · 2024
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  17. Functional Properties of Meat in Athletes' Performance and Recovery.International journal of environmental research and public health · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Chutimon KhemtongInstitute of Sports Sciences, University of Taipei, 101 Zhongcheng Rd. Section 2, Shilin District, Taipei 111, Taiwan.ORCID 0000-0002-1924-561X
Chia-Hua KuoInstitute of Sports Sciences, University of Taipei, 101 Zhongcheng Rd. Section 2, Shilin District, Taipei 111, Taiwan.ORCID 0000-0002-1731-4984
Chih-Yen ChenDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Salvador J JaimeDepartment of Exercise and Sport Science, University of Wisconsin-La Crosse, La Crosse, WI 54601, USA.
Giancarlo CondelloInstitute of Sports Sciences, University of Taipei, 101 Zhongcheng Rd. Section 2, Shilin District, Taipei 111, Taiwan.ORCID 0000-0001-5092-3258
University of Taipei · TWNational Yang Ming Chiao Tung University · TWUniversity of Wisconsin–La Crosse · US

Funding

Ministry of Science and Technology, Taiwan MOST 108-2410-H-845-023-MY2
6 · The paper itself

Abstract

Previous studies have reported the positive effects of branched-chain amino acids (BCAAs) supplementation on lowering plasma markers of muscle damage and subjective soreness after resistance exercise. However, a variety of factors can potentially moderate its efficacy. This meta-analysis aimed to summarize the evidence regarding the effect of BCAAs supplementation on plasma muscle damage markers and soreness after resistance exercise in only trained males, by considering the plasma lactate dehydrogenase (LDH) and creatine kinase (CK). Randomized controlled trials were identified through a computerized literature search for the period 2010-2020. The pooled data were analyzed with the random-effects model and heterogeneity using

Indexed as

Amino Acids, Branched-ChainDietary SupplementsAdultAthletesHumansMaleMuscle, SkeletalMyalgiaRandomized Controlled Trials as TopicYoung AdultAmino Acids, Branched-Chainbranched-chain amino acidscreatine kinaseinflammatory responselactate dehydrogenasemeta-analysismuscle damagemuscle sorenessresistance exercise

Identifiers

PMID34072718
PMCPMC8230327
OpenAlexW3164849432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.