Evidence map›Paper›PMID 34072700›Full record

ReviewMolecules (Basel, Switzerland)2021

Advances in Nanodelivery of Green Tea Catechins to Enhance the Anticancer Activity.

Yike Jiang, Ziyi Jiang, Lan Ma, Qingrong Huang

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. A Mussel-Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Green Tea: Current Knowledge and Issues.Foods (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. NanoInternational journal of nanomedicine · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yike JiangShenzhen Bay Laboratory, Institute of Biomedical Health Technology and Engineering, Shenzhen 518132, China.ORCID 0000-0002-6501-0475
Ziyi JiangInstitute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Lan MaShenzhen Bay Laboratory, Institute of Biomedical Health Technology and Engineering, Shenzhen 518132, China.ORCID 0000-0002-6610-5871
Qingrong HuangDepartment of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, NJ 08901, USA.
Shenzhen Bay Laboratory · CNRutgers, The State University of New Jersey · USTsinghua–Berkeley Shenzhen Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading causes of death globally. A variety of phenolic compounds display preventative and therapeutic effects against cancers. Green teas are rich in phenolics. Catechins are the most dominant phenolic component in green teas. Studies have shown that catechins have anticancer activity in various cancer models. The anticancer activity of catechins, however, may be compromised due to their low oral bioavailability. Nanodelivery emerges as a promising way to improve the oral bioavailability and anticancer activity of catechins. Research in this area has been actively conducted in recent decades. This review provides the molecular mechanisms of the anticancer effects of catechins, the factors that limit the oral bioavailability of catechins, and the latest advances of delivering catechins using nanodelivery systems through different routes to enhance their anticancer activity.

Indexed as

TeaAdministration, OralAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsCatechinCell CycleCell ProliferationDrug CarriersDrug Delivery SystemsGastrointestinal MicrobiomeHumansLipidsMiceAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsCatechinDrug CarriersLipidsPhenolTeaanticancer activitycatechinsgreen teananodelivery systemphenolic compounds

Identifiers

PMID34072700
PMCPMC8198522
OpenAlexW3164190685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.