ReviewPolymers2021
Collagen Matrix vs. Autogenous Connective Tissue Graft for Soft Tissue Augmentation: A Systematic Review and Meta-Analysis.
Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06880185 (Effects of Ribose Cross-Linked Thick Collagen Membranes and Connective Tissue Grafts on Peri-Implant Tissue), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Ribose Cross-Linked Thick Collagen Membranes and Connective Tissue Grafts on Peri-Implant Tissue
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy of Xenogeneic Collagen Matrices in Augmenting Peri-Implant Soft Tissue: A Systematic Review and Meta-Analysis.Clinical and experimental dental research · 2024Pooled it
- Comparative analysis of xenogeneic collagen matrix and autogenous subepithelial connective tissue graft to increase soft tissue volume around dental implants: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Comparison of the efficacy and long-term stability of tunnel technique and coronally advanced flap in the treatment of gingival recession: a Meta-analysis.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2023Pooled it
- Modified vascularized interpositional periosteal connective tissue graft versus xenogeneic collagen matrix for soft tissue augmentation around implant in esthetic zone (A comparative Study).BMC oral health · 2025Trial
- 3D-Analysis of Peri-Implant Soft Tissue Gain With Collagen Matrix and Connective Tissue Graft: A Randomized Control Trial.Clinical implant dentistry and related research · 2025Trial
- Connective tissue graft versus xenogeneic collagen matrix for soft tissue augmentation at implant sites: a randomized-controlled clinical trial.Clinical oral investigations · 2022Trial
- Review
- Comparative Histological Evaluation of Collagen Matrix Architectures for Soft Tissue Augmentation in the Oral Cavity: A Preclinical Canine Model.Bioengineering (Basel, Switzerland) · 2026Article
- Soft Tissue Augmentation in Periodontics and Implantology: Current Concepts, Techniques, and Clinical Outcomes.Cureus · 2026Review
- Mechanical and Biological Properties of Nondecellularized Human Wharton's Jelly Matrix for Soft Tissue Graft Material: An In Vitro Study.European journal of dentistry · 2026Article
- Preparation protocols and periodontal applications of platelet rich fibrin, a review.Frontiers in dental medicine · 2026Review
- Mandibular Rotated Pediculated Flap: A Technique to Increase Peri-Implant Mucosa Thickness.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Article
- Gene Therapeutic Drug pCMV-VEGF165 Plasmid ('Neovasculgen') Promotes Gingiva Soft Tissue Augmentation in Rabbits.International journal of molecular sciences · 2024Article
- Biomaterials in Medical Applications.Polymers · 2023Article
- Management of inadequate width of attached gingiva using mucograft.Journal of advanced pharmaceutical technology & research · 2022Article
- Preliminary study of silk fibroin porous scaffold for oral soft-tissue thickening.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- A regulatory perspective on recombinant collagen-based medical devices.Bioactive materials · 2022Article
- Histomorphometric Analysis of Differential Regional Bone Regeneration Induced by Distinct Doped Membranes.Polymers · 2022Article
- Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Soft tissues have been shown to be critical for the maintenance of both teeth and implants. Currently, regenerative soft tissue techniques propose the use of collagen matrices, which can avoid the drawbacks derived from the obtainment of autogenous tissue graft. A systematic review and meta-analysis were conducted to ascertain the efficacy of collagen matrices (CM) compared to autogenous connective tissue graft (CTG) to improve soft tissue dimensions. An electronic and manual literature searches were performed to identify randomized clinical trials (RCT) or controlled clinical trials (CCT) that compared CTG and CM. Pooled data of width of keratinized tissue (KT) and mucosal thickness (MT) were collected and weighted means were calculated. Heterogeneity was determined using Higgins (I
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.