Evidence map›Paper›PMID 34072635›Full record

ArticleHealthcare (Basel, Switzerland)2021

Hepatitis C Virus Prevalence and Risk Factors in a Village in Northeastern Romania-A Population-Based Screening-The First Step to Viral Micro-Elimination.

Laura Huiban, Carol Stanciu, Cristina Maria Muzica, Tudor Cuciureanu, Stefan Chiriac, Sebastian Zenovia, Vladut Mirel Burduloi, Oana Petrea, Ana Maria Sîngeap, Irina Gîrleanu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Prevalence of chronic hepatitis C infection in the general population: results from a national survey, Romania, 2020 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Laura HuibanDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.
Carol StanciuDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.
Cristina Maria MuzicaDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-0891-5961
Tudor CuciureanuDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.
Stefan ChiriacDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-2497-9236
Sebastian ZenoviaDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-0441-3980
Vladut Mirel BurduloiDepartment of Anatomy "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.
Oana PetreaDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-4698-1548
Ana Maria SîngeapDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-5621-548X
Irina GîrleanuDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-5925-1232
Cătălin SfartiDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.
Camelia CojocariuDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.
Anca TrifanDepartment of Gastroenterology "Grigore T. Popa", University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-9144-5520
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The World Health Organization adopted a strategy for the Global Health Sector on Viral Hepatitis in 2016, with the main objective of eliminating hepatitis C virus (HCV) by 2030. In this work, we aimed to evaluate the prevalence of HCV infection and risk factors in a Romanian village using population-based screening as part of the global C virus eradication program. (2) Methods: We conducted a prospective study from March 2019 to February 2020, based on a strategy as part of a project designed to educate, screen, treat and eliminate HCV infection in all adults in a village located in Northeastern Romania. (3) Results: In total, 3507 subjects were invited to be screened by rapid diagnostic orientation tests (RDOT). Overall, 2945 (84%) subjects were tested, out of whom 78 (2.64%) were found to have positive HCV antibodies and were scheduled for further evaluation in a tertiary center of gastroenterology/hepatology in order to be linked to care. In total, 66 (85%) subjects presented for evaluation and 55 (83%) had detectable HCV RNA. Of these, 54 (98%) completed antiviral treatment and 53 (99%) obtained a sustained virological response. (4) Conclusions: The elimination of hepatitis C worldwide has a higher chance of success if micro-elimination strategies based on mass screening are adopted.

Indexed as

cascade of carehealth policyhepatitis C virus treatmentmicro-eliminationscreening

Identifiers

PMID34072635
PMCPMC8229891
OpenAlexW3164643227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.