Evidence map›Paper›PMID 34072618›Full record

ReviewInternational journal of molecular sciences2021

The Evolution of Rag Gene Enhancers and Transcription Factor E and Id Proteins in the Adaptive Immune System.

Genki Yoshikawa, Kazuko Miyazaki, Hiroyuki Ogata, Masaki Miyazaki

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Genetic Variation in Transcription Factor Binding Sites.International journal of molecular sciences · 2023
    Article
  3. E protein binding at theFrontiers in immunology · 2023
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Genki YoshikawaBioinformatics Center, Institute for Chemical Research, Kyoto University, Uji 611-0011, Japan.
Kazuko MiyazakiLaboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Hiroyuki OgataBioinformatics Center, Institute for Chemical Research, Kyoto University, Uji 611-0011, Japan.ORCID 0000-0001-6594-377X
Masaki MiyazakiLaboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.ORCID 0000-0002-9543-624X
Kyoto University · JP

Funding

Japan Society for the Promotion of Science 19H03487
6 · The paper itself

Abstract

Adaptive immunity relies on the V(D)J DNA recombination of immunoglobulin (

Indexed as

Enhancer Elements, GeneticEvolution, MolecularAdaptive ImmunityAnimalsB-LymphocytesCell DifferentiationGene Expression RegulationHomeodomain ProteinsHumansRegulatory Sequences, Nucleic AcidT-LymphocytesTranscription FactorsV(D)J RecombinationHomeodomain ProteinsTranscription Factorsadaptive immune systembHLH transcription factorsE proteinId proteinRag1/2 gene enhancersT and B cell development

Identifiers

PMID34072618
PMCPMC8199221
OpenAlexW3165761074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.