Evidence map›Paper›PMID 34072560›Full record

ArticleInternational journal of molecular sciences2021

Arylamine Analogs of Methylene Blue: Substituent Effect on Aggregation Behavior and DNA Binding.

Alena Khadieva, Olga Mostovaya, Pavel Padnya, Valeriy Kalinin, Denis Grishaev, Dmitrii Tumakov, Ivan Stoikov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Design, Spectral Insights, and Enhanced Antioxidant Potential of Novel Phenothiazine DerivativesAnti-inflammatory & anti-allergy agents in medicinal chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alena KhadievaA.M. Butlerov' Chemistry Institute of Kazan Federal University, 18 Kremlyovskaya Str., 420008 Kazan, Russia.
Olga MostovayaA.M. Butlerov' Chemistry Institute of Kazan Federal University, 18 Kremlyovskaya Str., 420008 Kazan, Russia.
Pavel PadnyaA.M. Butlerov' Chemistry Institute of Kazan Federal University, 18 Kremlyovskaya Str., 420008 Kazan, Russia.ORCID 0000-0002-1924-8028
Valeriy KalininA.M. Butlerov' Chemistry Institute of Kazan Federal University, 18 Kremlyovskaya Str., 420008 Kazan, Russia.ORCID 0000-0002-8425-9540
Denis GrishaevScientific and Educational Center of Pharmaceutics, Kazan Federal University, 420008 Kazan, Russia.
Dmitrii TumakovInstitute of Computational Mathematics and Information Technologies, Kazan Federal University, 420008 Kazan, Russia.ORCID 0000-0003-0564-8335
Ivan StoikovA.M. Butlerov' Chemistry Institute of Kazan Federal University, 18 Kremlyovskaya Str., 420008 Kazan, Russia.ORCID 0000-0002-3019-7866
Kazan Federal University · RU

Funding

Russian Foundation for Basic Research 19-33-90092
6 · The paper itself

Abstract

The synthesis of new phenothiazine derivatives, analogs of Methylene Blue, is of particular interest in the design of new drugs, as well as in the development of a new generation of agents for photodynamic therapy. In this study, two new derivatives of phenothiazine, i.e., 3,7-bis(4-aminophenylamino)phenothiazin-5-ium chloride dihydrochloride (

Indexed as

AminesDimerizationDNAIntercalating AgentsMagnetic Resonance SpectroscopyMethylene BlueModels, MolecularMolecular ConformationMolecular StructureSpectrometry, FluorescenceStructure-Activity RelationshipAminesDNAIntercalating AgentsMethylene Blue3,7-bis(N-phenylamino)phenothiazin-5-iumsdimerizationDNAintercalationmethylene bluephenothiazine

Identifiers

PMID34072560
PMCPMC8198855
OpenAlexW3164113579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.