ArticleCancers2021
Primary Gastrointestinal T/NK Cell Lymphoma.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Epidemiological and clinical trends of malignant small-bowel tumors in Asia.The Korean journal of internal medicine · 2026Review
- A 21-year-old man with anemia and gastrointestinal bleeding caused by jejunal EBV-associated T/natural killer-cell lymphoproliferative disorder.Clinical journal of gastroenterology · 2026Article
- Clinicopathological characteristics of a rare group of chronic active Epstein-Barr virus disease involving the gastrointestinal tract.Journal of hematopathology · 2026Article
- The CT findings of extranodal natural killer/T-cell lymphoma, nasal type involving the gastrointestinal tract.European radiology · 2025Article
- Case Report: diffuse entire gastrointestinal tract involvement of ALK-positive anaplastic large cell lymphoma harboring JAK-STAT pathway mutations in an adolescent with leukemoid reaction.Frontiers in oncology · 2025Article
- Differentiating small intestinal stromal tumors from primary small intestinal lymphomas using contrast-enhanced CT and texture analysis: a diagnostic study.Frontiers in oncology · 2025Article
- Comparison of clinical features of patients with or without severe gastrointestinal complications in aggressive gastrointestinal lymphomas.World journal of gastrointestinal oncology · 2024Article
- A rare case of monomorphic epitheliotropic intestinal T-cell lymphoma, presenting with spontaneous intestinal perforation.International journal of surgery case reports · 2024Article
- A Rare Case of Gastric Extranodal NK/T-Cell Lymphoma With Orbital Involvement.ACG case reports journal · 2024Article
- Clinical and Histopathological Features of an Italian Monocentric Series of Primary Small Bowel T-Cell Lymphomas.Cancers · 2023Article
- Gastric CD56-negative Extranodal Natural Killer/T-cell Lymphoma: A Case Report.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Article
- Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary gastrointestinal T/NK cell lymphoma (GI-TNKL) is an uncommon and heterogeneous group of lymphoid malignancies. We aimed to investigate their subtype distribution, clinicopathologic characteristics, and clinical outcomes. A total of 38 GI-TNKL cases and their clinical and pathological characteristics were analyzed. GI-TNKL occurred in adults with a median patient age in the sixth decade of life and showed a slight male predominance. The most common histologic type was extranodal NK/T-cell lymphoma, nasal type (ENKTL; 34.2%), followed by monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL; 31.6%), intestinal T-cell lymphoma, NOS (ITCL, NOS, 18.4%), anaplastic large cell lymphoma, ALK-negative (ALCL, ALK-; 13.2%). The small intestine was the primary affected region. More than 90% of patients complained of various GI symptoms and cases with advanced Lugano stage, high IPI score, or bowel perforation that required emergent operation were not uncommon. GI-TNKL also showed aggressive behavior with short progression-free survival and overall survival. This thorough clinical and pathological descriptive analysis will be helpful for accurate understanding, diagnosis, and treatment.
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