Evidence map›Paper›PMID 34072257›Full record

ReviewCancers2021

Decoding LncRNAs.

Lidia Borkiewicz, Joanna Kalafut, Karolina Dudziak, Alicja Przybyszewska-Podstawka, Ilona Telejko

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
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  5. Article
  6. Review
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  8. The role of curcumin in modulating circular RNAs and long non-coding RNAs in cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Non-Coding RNAs in Breast Cancer: Diagnostic and Therapeutic Implications.International journal of molecular sciences · 2024
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lidia BorkiewiczDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-059 Lublin, Poland.
Joanna KalafutDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-7452-8874
Karolina DudziakDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-059 Lublin, Poland.
Alicja Przybyszewska-PodstawkaDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0003-1611-7994
Ilona TelejkoDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-059 Lublin, Poland.

Funding

Narodowa Agencja Wymiany Akademickiej PPI/APM/2019/1/00089/DEC/1Narodowe Centrum Nauki DEC-2017/25/B/NZ4/02364
6 · The paper itself

Abstract

Non-coding RNAs (ncRNAs) have been considered as unimportant additions to the transcriptome. Yet, in light of numerous studies, it has become clear that ncRNAs play important roles in development, health and disease. Long-ignored, long non-coding RNAs (lncRNAs), ncRNAs made of more than 200 nucleotides have gained attention due to their involvement as drivers or suppressors of a myriad of tumours. The detailed understanding of some of their functions, structures and interactomes has been the result of interdisciplinary efforts, as in many cases, new methods need to be created or adapted to characterise these molecules. Unlike most reviews on lncRNAs, we summarize the achievements on lncRNA studies by taking into consideration the approaches for identification of lncRNA functions, interactomes, and structural arrangements. We also provide information about the recent data on the involvement of lncRNAs in diseases and present applications of these molecules, especially in medicine.

Indexed as

biomarkersgene regulationgene therapylncRNAmiRNA sponge

Identifiers

PMID34072257
PMCPMC8199187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.