Evidence map›Paper›PMID 34072132›Full record

ArticleGenes2021

Comparison of Selection Signatures between Korean Native and Commercial Chickens Using 600K SNP Array Data.

Sunghyun Cho, Prabuddha Manjula, Minjun Kim, Eunjin Cho, Dooho Lee, Seung Hwan Lee, Jun Heon Lee, Dongwon Seo

Abstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sunghyun ChoDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Prabuddha ManjulaDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Minjun KimDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Eunjin ChoDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Dooho LeeDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Seung Hwan LeeDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Jun Heon LeeDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0003-3996-9209
Dongwon SeoDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Korean native chickens (KNCs) comprise an indigenous chicken breed of South Korea that was restored through a government project in the 1990s. The KNC population has not been developed well and has mostly been used to maintain purebred populations in the government research institution. We investigated the genetic features of the KNC population in a selection signal study for the efficient improvement of this breed. We used 600K single nucleotide polymorphism data sampled from 191 KNCs (NG, 38; NL, 29; NR, 52; NW, 39; and NY, 33) and 54 commercial chickens (Hy-line Brown, 10; Lohmann Brown, 10; Arbor Acres, 10; Cobb, 12; and Ross, 12). Haplotype phasing was performed using EAGLE software as the initial step for the primary data analysis. Pre-processed data were analyzed to detect selection signals using the 'rehh' package in R software. A few common signatures of selection were identified in KNCs. Most quantitative trait locus regions identified as candidate regions were associated with traits related to reproductive organs, eggshell characteristics, immunity, and organ development. Block patterns with high linkage disequilibrium values were observed for LPP, IGF11, LMNB2, ERBB4, GABRB2, NTM, APOO, PLOA1, CNTN1, NTSR1, DEF3, CELF1, and MEF2D genes, among regions with confirmed selection signals. NL and NW lines contained a considerable number of selective sweep regions related to broilers and layers, respectively. We recommend focusing on improving the egg and meat traits of KNC NL and NW lines, respectively, while improving multiple traits for the other lines.

Indexed as

Polymorphism, Single NucleotideSelection, GeneticSelective BreedingAnimalsAvian ProteinsChickensHaplotypesQuantitative Trait LociAvian ProteinsKorean native chickenquantitative trait locussignature of selection

Identifiers

PMID34072132
PMCPMC8230197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.