Evidence map›Paper›PMID 34072005›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

Genomic Markers for Essential Tremor.

Félix Javier Jiménez-Jiménez, Hortensia Alonso-Navarro, Elena García-Martín, Ignacio Álvarez, Pau Pastor, José A G Agúndez

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Tremor pathophysiology.Clinical parkinsonism & related disorders · 2026
    Review
  3. Copy Number Variant Duplications Associated with Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Association Between Common Variants in theInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. A NovelGenes · 2023
    Article
  13. Han family with essential tremor caused by the P421L variant of the TENM4 gene in China.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  14. Article
  15. Article
  16. Non-motor features of essential tremor with midline distribution.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Félix Javier Jiménez-JiménezSection of Neurology, Hospital Universitario del Sureste, E28500 Arganda del Rey, Spain.ORCID 0000-0002-7558-7323
Hortensia Alonso-NavarroSection of Neurology, Hospital Universitario del Sureste, E28500 Arganda del Rey, Spain.
Elena García-MartínARADyAL Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, University of Extremadura, E10071 Caceres, Spain.
Ignacio ÁlvarezMovement Disorders Unit, Department of Neurology, University Hospital Mútua de Terrassa, Fundació Docencia i Recerça Mútua de Terrassa, E08221 Terrassa, Spain.
Pau PastorMovement Disorders Unit, Department of Neurology, University Hospital Mútua de Terrassa, Fundació Docencia i Recerça Mútua de Terrassa, E08221 Terrassa, Spain.
José A G AgúndezARADyAL Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, University of Extremadura, E10071 Caceres, Spain.
Hospital Universitario del Sureste · ESInstituto de Salud Carlos III · ESUniversity Hospital Mútua de Terrassa · ES

Funding

Instituto de Salud Carlos III, Madrid, Spain PI15/00303Instituto de Salud Carlos III, Madrid, Spain PI18/00540Instituto de Salud Carlos III, Madrid, Spain RETICS RD16/0006/0004 (ARADyAL)Junta de Extremadura, Mérida, Spain GR18145Junta de Extremadura, Mérida, Spain IB16170
6 · The paper itself

Abstract

There are many reports suggesting an important role of genetic factors in the etiopathogenesis of essential tremor (ET), encouraging continuing the research for possible genetic markers. Linkage studies in families with ET have identified 4 genes/loci for familial ET, although the responsible gene(s) have not been identified. Genome-wide association studies (GWAS) described several variants in

Indexed as

essential tremorfamily historygenetic polymorphismsgeneticslinkage studies

Identifiers

PMID34072005
PMCPMC8226734
OpenAlexW3165325330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.