ArticleJournal of clinical medicine2021
Endoscopic Vacuum Therapy in Patients with Transmural Defects of the Upper Gastrointestinal Tract: A Systematic Review with Meta-Analysis.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Management of iatrogenic esophageal perforations: a systematic review of non-surgical causes.Surgical endoscopy · 2026Pooled it
- Fatal cerebral gas embolism during endoluminal vacuum therapy for esophageal leak.Clinical journal of gastroenterology · 2026Article
- [Catheter ablation-induced esophageal complications].Herzschrittmachertherapie & Elektrophysiologie · 2026Review
- Endoscopic vacuum therapy for gastrointestinal transmural defects: clinical outcomes and treatment implications: a retrospective study from Korea.Ewha medical journal · 2026Article
- Stents and Emerging Alternatives in Upper Gastrointestinal Endoscopy: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2025Review
- Suture traction-assisted bearclaw fistula closure: a case series describing a novel endoscopic technique for fistula closure.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025Article
- Endoscopic Vacuum Therapy for Anastomotic Leakage After Distal Gastrectomy in a Renal Transplant Patient: A Case Study.The American journal of case reports · 2025Article
- Comprehensive Umbrella Review of the Management of Esophageal Anastomotic Leaks.Journal of clinical medicine · 2025Review
- Endoscopic Vacuum Therapy for the Treatment of Atrial Fibrillation Ablation-Induced Esophageal Perforation.ACG case reports journal · 2025Article
- Endoscopic vacuum therapy for gastrointestinal transmural defects: a literature review.Clinical endoscopy · 2025Review
- Endoscopic vacuum therapy.iGIE : innovation, investigation and insights · 2024Article
- Additional over-the-scope-clip closure can shorten endoscopic vacuum therapy for postoperative upper gastrointestinal leakage.Endoscopy international open · 2024Article
- The Role of Open-Pore Film Drainage Systems in Endoscopic Vacuum Therapy: Current Status and Review of the Literature.Visceral medicine · 2024Review
- Endoscopic vacuum therapy: 2 methods of successful endosponge placement for treatment of anastomotic leak in the upper GI tract.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023Article
- Endoscopic Vacuum Therapy of Upper Gastrointestinal Anastomotic Leaks: How to Deal with the Challenges (with Video).Life (Basel, Switzerland) · 2023Review
- Applications of endoscopic vacuum therapy in the upper gastrointestinal tract.World journal of gastrointestinal endoscopy · 2023Review
- Endoscopic Management of Postoperative Esophageal and Upper GI Defects-A Narrative Review.Medicina (Kaunas, Lithuania) · 2023Review
- Management of aero-digestive fistulas: the gastroenterologist's perspective, a narrative review.Mediastinum (Hong Kong, China) · 2023Review
- Clinical implantation of 92 VACStents in the upper gastrointestinal tract of 50 patients-applicability and safety analysis of an innovative endoscopic concept.Frontiers in surgery · 2023Article
- Endoscopic negative pressure therapy for duodenal leaks.Frontiers in surgery · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A transmural defect of the upper gastrointestinal (UGI) tract is a life-threatening condition associated with high morbidity and mortality. Recently, endoscopic vacuum therapy (EVT) was used for managing UGI defects and showed promising results. We conducted a systematic review and meta-analysis to synthesize evidence on the efficacy of EVT in patients with transmural defects of the UGI tract. We searched the PubMed, Cochrane Library, and Embase databases for publications on the effect of EVT on successful closure, mortality, complications, and post-EVT strictures. Methodological quality was assessed using the Newcastle-Ottawa quality assessment scale. This meta-analysis included 29 studies involving 498 participants. The pooled estimate rate of successful closure with EVT was 0.85 (95% confidence interval [CI]: 0.81-0.88). The pooled estimate rates for mortality, complications, and post-EVT strictures were 0.11, 0.10, and 0.14, respectively. According to the etiology of the transmural defect (perforation vs. leak and fistula), no significant difference was observed in successful closure (odds ratio [OR]: 1.45, 95% CI: 0.45-4.67,
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Registered trials
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