Evidence map›Paper›PMID 34071806›Full record

ReviewInsects2021

(Epi)Genetic Mechanisms Underlying the Evolutionary Success of Eusocial Insects.

Kayli R Sieber, Taylor Dorman, Nicholas Newell, Hua Yan

Open access · goldAbstract readReview
In one paragraph

Review in Insects, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Review
  3. EpiBrain: the brain's epigenetic landscape in a snapshot.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Climate change-induced stress in the honey beeFrontiers in physiology · 2025
    Review
  7. The Molecular Substrates of Insect Eusociality.Annual review of genetics · 2024
    Review
  8. Pervasive relaxed selection in termite genomes.Proceedings. Biological sciences · 2024
    Article
  9. Neuromodulators and neuroepigenetics of social behavior in ants.Annals of the New York Academy of Sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kayli R SieberDepartment of Biology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-3493-3290
Taylor DormanDepartment of Biology, University of Florida, Gainesville, FL 32611, USA.
Nicholas NewellDepartment of Biology, University of Florida, Gainesville, FL 32611, USA.
Hua YanDepartment of Biology, University of Florida, Gainesville, FL 32611, USA.
University of Florida · US

Funding

Training Program in Chemosensory ScienceT32DC015994 · NIDCD · UNIVERSITY OF FLORIDA · PI Daniel W Wesson · 2018 to 2026
$1.4M
Center for Arthropod Management Technologies IIP-1821914NIDCD NIH HHS T32 DC015994
6 · The paper itself

Abstract

Eusocial insects, such as bees, ants, and wasps of the Hymenoptera and termites of the Blattodea, are able to generate remarkable diversity in morphology and behavior despite being genetically uniform within a colony. Most eusocial insect species display caste structures in which reproductive ability is possessed by a single or a few queens while all other colony members act as workers. However, in some species, caste structure is somewhat plastic, and individuals may switch from one caste or behavioral phenotype to another in response to certain environmental cues. As different castes normally share a common genetic background, it is believed that much of this observed within-colony diversity results from transcriptional differences between individuals. This suggests that epigenetic mechanisms, featured by modified gene expression without changing genes themselves, may play an important role in eusocial insects. Indeed, epigenetic mechanisms such as DNA methylation, histone modifications and non-coding RNAs, have been shown to influence eusocial insects in multiple aspects, along with typical genetic regulation. This review summarizes the most recent findings regarding such mechanisms and their diverse roles in eusocial insects.

Indexed as

behavioral plasticityepigeneticseusocial insectsevolution

Identifiers

PMID34071806
PMCPMC8229086
OpenAlexW3165266514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.