Evidence map›Paper›PMID 34071761›Full record

ArticleCancers2021

Dynein Light Chain Protein Tctex1: A Novel Prognostic Marker and Molecular Mediator in Glioblastoma.

Claudia Alexandra Dumitru, Eileen Brouwer, Tamina Stelzer, Salvatore Nocerino, Sebastian Rading, Ludwig Wilkens, Ibrahim Erol Sandalcioglu, Meliha Karsak

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudia Alexandra DumitruDepartment of Neurosurgery, Otto-von-Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0003-2075-9164
Eileen BrouwerCenter for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.
Tamina StelzerCenter for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.
Salvatore NocerinoCenter for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.
Sebastian RadingCenter for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.
Ludwig WilkensDepartment of Pathology, Nordstadt Hospital Hannover, 30167 Hannover, Germany.
Ibrahim Erol SandalciogluDepartment of Neurosurgery, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Meliha KarsakCenter for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.ORCID 0000-0001-6612-6317

Funding

Werner Otto Stiftung 8/92
6 · The paper itself

Abstract

The purpose of this study was to determine the role of Tctex1 (DYNLT1, dynein light chain-1) in the pathophysiology of glioblastoma (GBM). To this end, we performed immunohistochemical analyses on tissues from GBM patients (

Indexed as

glioblastomaprognostic biomarkersTctex1/DYNLT1tumor invasiontumor proliferation

Identifiers

PMID34071761
PMCPMC8199143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.