Evidence map›Paper›PMID 34071751›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Pharmacological and Clinical Significance of Heme Oxygenase-1.

David E Stec, Nader G Abraham

Abstract readEditorial
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Heme oxygenase-1 and malaria pathogenesis.Frontiers in immunology · 2026
    Review
  2. Altered Expression of Heme Oxygenase 2 in Heme Oxygenase 1-deficient Mouse Embryos.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023
    Article
  3. Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2.Antioxidants (Basel, Switzerland) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David E StecDepartment of Physiology and Biophysics, Cardiorenal and Metabolic Diseases Research Center, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0001-8359-4008
Nader G AbrahamDepartment of Medicine, New York Medical College, Valhalla, NY 10595, USA.ORCID 0000-0001-8983-1959

Funding

The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Integrative Role of Bilirubin on ObesityR01DK121748 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI STEC, DAVID E · 2020 to 2023
$2.0M
Adipocyte EET-PGC1alpha-HO-1 in Obesity-driven HypertensionR56HL139561 · NHLBI · NEW YORK MEDICAL COLLEGE · PI ABRAHAM, NADER G. · 2018 to 2018
$503k
NHLBI NIH HHS R56 HL139561NIDDK NIH HHS R01 DK121748NIGMS NIH HHS P20GM104357-02 (DES)NIH HHS R 56-139561 (NGA), 1R01DK126884-01 (DES) 1R01DK121797-01A1 (DES), P01 HL05197-11 (DES)
6 · The paper itself

Abstract

This Special Issue collates and updates the current knowledge of the pharmacology and clinical applications concerning the enzyme heme oxygenase (HO) [...].

Identifiers

PMID34071751
PMCPMC8227735

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.