Evidence map›Paper›PMID 34071724›Full record

ArticlePathogens (Basel, Switzerland)2021

Survey of Viral Reactivations in Elite Athletes: A Case-Control Study.

Lari Pyöriä, Maarit Valtonen, Raakel Luoto, Wilma Grönroos, Matti Waris, Olli J Heinonen, Olli Ruuskanen, Maria F Perdomo

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lari PyöriäDepartment of Virology, University of Helsinki, 00290 Helsinki, Finland.
Maarit ValtonenResearch Institute for Olympics Sports, 40700 Jyväskylä, Finland.
Raakel LuotoDepartment of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, 20521 Turku, Finland.ORCID 0000-0001-5752-7047
Wilma GrönroosPaavo Nurmi Centre and Unit of Health and Physical Activity, University of Turku, 20520 Turku, Finland.
Matti WarisInstitute of Biomedicine, University of Turku and Department of Clinical Microbiology, Turku University Hospital, 20520 Turku, Finland.
Olli J HeinonenPaavo Nurmi Centre and Unit of Health and Physical Activity, University of Turku, 20520 Turku, Finland.
Olli RuuskanenDepartment of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, 20521 Turku, Finland.
Maria F PerdomoDepartment of Virology, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0002-9031-4251
University of Turku · FIUniversity of Helsinki · FIResearch Institute for Olympic Sports · FI

Funding

Biomedicum Helsinki-säätiöFinska LäkaresällskapetInstrumentariumin TiedesäätiöJenny ja Antti Wihurin RahastoMedicinska Understödsföreningen Liv och HälsaSuomen KulttuurirahastoSuomen Lääketieteen Säätiö 3387
6 · The paper itself

Abstract

Exercise-induced immune perturbations have been proposed to increase susceptibility to viral infections. We investigated the replication of persisting viruses as indicators of immune function in elite cross-country skiers after ten months of sustained high-performance exercise. The viruses evaluated, nine human herpesviruses (HHVs) and torque teno virus (TTV), are typically restrained in health but replicate actively in immunosuppressed individuals. We collected sera from 27 Finnish elite cross-country skiers at the end of the competition's season and 27 matched controls who perform moderate exercise. We quantified all the HHVs and-TTV via highly sensitive qPCRs. To verify equal past exposures between the groups, we assessed the IgG antibody prevalences toward HHV-4 (Epstein-Barr virus, EBV) and HHV-5 (human cytomegalovirus, HCMV). We found equal TTV DNA prevalences in athletes (63%) and controls (63%) and loads with respective geometric means of 1.7 × 10

Indexed as

elite athletesHHVimmunocompetenceTTVviral immunity

Identifiers

PMID34071724
PMCPMC8229584
OpenAlexW3164775171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.