Evidence map›Paper›PMID 34071612›Full record

ArticleMolecules (Basel, Switzerland)2021

A Non-Invasive Hair Test to Determine Vitamin D

Iltaf Shah, Mohammad Mansour, Sheikh Jobe, Emadaldeen Salih, Declan Naughton, Syed Salman Ashraf

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Iltaf ShahDepartment of Chemistry, College of Science, UAE University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0002-3739-6083
Mohammad MansourDepartment of Chemistry, College of Science, UAE University, Al Ain P.O. Box 15551, United Arab Emirates.
Sheikh JobeDepartment of Chemistry, College of Science, UAE University, Al Ain P.O. Box 15551, United Arab Emirates.
Emadaldeen SalihDepartment of Chemistry, College of Science, UAE University, Al Ain P.O. Box 15551, United Arab Emirates.
Declan NaughtonSchool of Life Sciences, Pharmacy and Chemistry, Kingston University London, Surrey KT1 2EE, UK.
Syed Salman AshrafDepartment of Chemistry, College of Arts and Sciences, Khalifa University, Abu Dhabi P.O. Box 127788, United Arab Emirates.ORCID 0000-0003-4961-5527
United Arab Emirates University · AEKhalifa University of Science and Technology · AEKingston University · GB

Funding

United Arab Emirates University 31S213
6 · The paper itself

Abstract

Vitamin D deficiency is being recognized as a global issue and has been implicated in many health issues. Hence, there is an increased interest in developing sensitive, reproducible, and non-invasive assays to measure Vitamin D levels. This study aimed to apply a sensitive liquid chromatography-mass spectrometric assay to hair samples to develop and validate a clinical assay to provide a quarterly average level of vitamin D in one test. Hair samples were collected from 70 male university students/young adults and pulverized/sonicated in methanol/water for 2 h to extract Vitamin D metabolites. A sensitive liquid chromatographic-mass spectrometric assay was employed to quantitate vitamin D and metabolites. Of the eight Vitamin D and metabolites screened, only the primary, clinically significant form of vitamin D (25OHD

Indexed as

Chemistry Techniques, AnalyticalHairAdolescentAdultCalibrationCholecalciferolChromatography, LiquidDisease ProgressionHumansLimit of DetectionMalePilot ProjectsReproducibility of ResultsSonicationTandem Mass SpectrometryVitamin DCholecalciferolVitamin Dhair analysesliquid chromatography-mass spectrometryvitamin D assay

Identifiers

PMID34071612
PMCPMC8198702
OpenAlexW3165559075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.