Evidence map›Paper›PMID 34071607›Full record

ArticleCancers2021

Phase I Trial of Prophylactic Donor-Derived IL-2-Activated NK Cell Infusion after Allogeneic Hematopoietic Stem Cell Transplantation from a Matched Sibling Donor.

Raynier Devillier, Boris Calmels, Sophie Guia, Mohammed Taha, Cyril Fauriat, Bechara Mfarrej, Geoffroy Venton, Eric Vivier, Daniel Olive, Christian Chabannon and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01853358 (Phase I of Infusion of Selected Donor NK Cells After HLA Identical Allogeneic Stem Cell Transplantation Prepared With Reduced Intensity Conditioning - DLI-NK/IPC 2012-003), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01853358 phase1completednot on this map

Phase I of Infusion of Selected Donor NK Cells After HLA Identical Allogeneic Stem Cell Transplantation Prepared With Reduced Intensity Conditioning - DLI-NK/IPC 2012-003

TypeinterventionalSponsorInstitut Paoli-CalmettesRan2013 to 2018Enrolled17ConditionsHematological MalignancyArmsNK Cell infusion
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. New immune cell engagers for cancer immunotherapy.Nature reviews. Immunology · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Raynier DevillierHematology Department, Institut Paoli-Calmettes, 13009 Marseille, France.
Boris CalmelsCRCM, Inserm Institut Paoli-Calmettes, Aix-Marseille Université, 13009 Marseille, France.
Sophie GuiaCentre d'Immunologie de Marseille-Luminy CIML, CNRS, INSERM, Aix Marseille Université, 13009 Marseille, France.ORCID 0000-0001-8405-4687
Mohammed TahaImmunity and Cancer Team, CRCM, Inserm Institut Paoli-Calmettes, Aix-Marseille Université, 13007 Marseille, France.
Cyril FauriatImmunity and Cancer Team, CRCM, Inserm Institut Paoli-Calmettes, Aix-Marseille Université, 13007 Marseille, France.
Bechara MfarrejCRCM, Inserm Institut Paoli-Calmettes, Aix-Marseille Université, 13009 Marseille, France.ORCID 0000-0002-8361-5240
Geoffroy VentonCentre d'Immunologie de Marseille-Luminy CIML, CNRS, INSERM, Aix Marseille Université, 13009 Marseille, France.
Eric VivierCentre d'Immunologie de Marseille-Luminy CIML, CNRS, INSERM, Aix Marseille Université, 13009 Marseille, France.ORCID 0000-0001-7022-8287
Daniel OliveImmunity and Cancer Team, CRCM, Inserm Institut Paoli-Calmettes, Aix-Marseille Université, 13007 Marseille, France.ORCID 0000-0003-1299-4113
Christian ChabannonCRCM, Inserm Institut Paoli-Calmettes, Aix-Marseille Université, 13009 Marseille, France.ORCID 0000-0002-3755-4889
Didier BlaiseHematology Department, Institut Paoli-Calmettes, 13009 Marseille, France.
Sophie UgoliniCentre d'Immunologie de Marseille-Luminy CIML, CNRS, INSERM, Aix Marseille Université, 13009 Marseille, France.ORCID 0000-0003-4041-0103
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

Institut National Du Cancer PHRC10_24-0
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

allogeneic hematopoietic stem cell transplantationantitumor immunitycellular immunotherapyIL-2-activated NK cells

Identifiers

PMID34071607
PMCPMC8198961
OpenAlexW3165594307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.