Evidence map›Paper›PMID 34071523›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Impact of FGFR4 Gene Polymorphism on the Progression of Colorectal Cancer.

Bei-Hao Shiu, Ming-Hong Hsieh, Wen-Chien Ting, Ming-Chih Chou, Lun-Ching Chang, Chi-Chou Huang, Shih-Chi Su, Shun-Fa Yang

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Frontiers in oncology · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Bei-Hao ShiuInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Ming-Hong HsiehInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.ORCID 0000-0002-3128-8110
Wen-Chien TingInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Ming-Chih ChouInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Lun-Ching ChangDepartment of Mathematical Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA.ORCID 0000-0002-8039-5350
Chi-Chou HuangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Shih-Chi SuWhole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung 204, Taiwan.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.ORCID 0000-0002-0365-7927
Chung Shan Medical University Hospital · TWChang Gung Memorial Hospital · TWFlorida Atlantic University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a multifactorial malignancy, and its high incidence and mortality rate remain a global public health burden. Fibroblast growth factor receptor 4 (FGFR4) is a receptor tyrosine kinase that has been shown to play a key role in cancer development and prognosis via the activation of its downstream oncogenic signaling pathways. The present study aimed to explore the impact of

Indexed as

colorectal cancerfibroblast growth factor receptor 4metastasissingle-nucleotide polymorphism

Identifiers

PMID34071523
PMCPMC8227855
OpenAlexW3164023653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.