Evidence map›Paper›PMID 34071371›Full record

ArticleInternational journal of molecular sciences2021

Molecular Genetics of Conjunctival Melanoma and Prognostic Value of

Natasha M van Poppelen, Jolique A van Ipenburg, Quincy van den Bosch, Jolanda Vaarwater, Tom Brands, Bert Eussen, Frank Magielsen, Hendrikus J Dubbink, Dion Paridaens, Erwin Brosens and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Ocular Melanoma: A Comprehensive Review with a Focus on Molecular Biology.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Incidence and Mortality of Conjunctival Melanoma in Australia (1982 to 2014).Investigative ophthalmology & visual science · 2023
    Article
  14. Article
  15. Review
  16. ATRX Loss in the Development and Prognosis of Conjunctival Melanoma.International journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Natasha M van PoppelenDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-6387-9997
Jolique A van IpenburgDepartment of Pathology, Section Ophthalmic Pathology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Quincy van den BoschDepartment of Pathology, Section Ophthalmic Pathology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Jolanda VaarwaterDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Tom BrandsDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Bert EussenDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Frank MagielsenDepartment of Clinical Genetics, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Hendrikus J DubbinkDepartment of Pathology, Section Ophthalmic Pathology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-2160-5207
Dion ParidaensDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-6762-3614
Erwin BrosensDepartment of Clinical Genetics, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-8235-4010
Nicole NausDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Annelies de KleinDepartment of Clinical Genetics, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Emine KiliçDepartment of Ophthalmology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Robert M VerdijkDepartment of Pathology, Section Ophthalmic Pathology, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1437-214X
Erasmus MC · NLLeiden University Medical Center · NLRadboud University Nijmegen · NL

Funding

KWF Kankerbestrijding 6905Stichting Nederlands Oogheelkundig Onderzoek 2013-2021Stichting Wetenschappelijk Oogheelkundig Onderzoek 2016-2017
6 · The paper itself

Abstract

The aim of this study was exploration of the genetic background of conjunctival melanoma (CM) and correlation with recurrent and metastatic disease. Twenty-eight CM from the Rotterdam Ocular Melanoma Study group were collected and DNA was isolated from the formalin-fixed paraffin embedded tissue. Targeted next-generation sequencing was performed using a panel covering

Indexed as

MutationAdolescentAdultAgedAged, 80 and overConjunctival NeoplasmsFemaleHigh-Throughput Nucleotide SequencingHumansKaplan-Meier EstimateMaleMelanomaMiddle AgedMolecular BiologyNeoplasm Recurrence, LocalPrognosisTelomeraseTERT protein, humanconjunctivamelanomamolecular medicineprognosisTERT promotor mutation

Identifiers

PMID34071371
PMCPMC8198138
OpenAlexW3164963267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.