Evidence map›Paper›PMID 34071088›Full record

ArticlePolymers2021

Double-Cross-Linked Networks Based on Methacryloyl Mucin.

Elena Olăreț, Brîndușa Bălănucă, Andra Mihaela Onaș, Jana Ghițman, Horia Iovu, Izabela-Cristina Stancu, Andrada Serafim

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elena OlărețAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0001-9593-6140
Brîndușa BălănucăAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0001-8600-3795
Andra Mihaela OnașAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.
Jana GhițmanAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.
Horia IovuAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.
Izabela-Cristina StancuAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.ORCID 0000-0003-0685-3947
Andrada SerafimAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Ghe. Polizu Street, 011061 Bucharest, Romania.
Universitatea Națională de Știință și Tehnologie Politehnica București · ROAcademia Oamenilor de Știință din România · RO

Funding

European Regional Development Fund P_36_611Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii PNIII-P1-1.1-TE-2019-1161Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii PN-III-P1-1.2-PCCDI-2017-0782/REGMED-project 2 NERVE
6 · The paper itself

Abstract

Mucin is a glycoprotein with proven potential in the biomaterials field, but its use is still underexploited for such applications. The present work aims to produce a synthesis of methacryloyl mucin single-network (SN) hydrogels and their double-cross-linked-network (DCN) counterparts. Following the synthesis of the mucin methacryloyl derivative, various SN hydrogels are prepared through the photopolymerization of methacrylate bonds, using reaction media with different pH values. The SN hydrogels are converted into DCN systems via supplementary cross-linking in tannic acid aqueous solution. The chemical modification of mucin is described, and the obtained product is characterized; the structural modification of mucin is assessed through FTIR spectroscopy, and the circular dichroism and the isoelectric point of methacryloyl mucin is evaluated. The affinity for aqueous media of both SN and DCN hydrogels is estimated, and the mechanical properties of the systems are assessed, both at macroscale through uniaxial compression and rheology tests and also at microscale through nanoindentation tests.

Indexed as

circular dichroismdouble-cross-linked networksmechanical characterizationmethacryloyl mucinporcine gastric mucin

Identifiers

PMID34071088
PMCPMC8197136
OpenAlexW3164878331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.