Evidence map›Paper›PMID 34071007›Full record

ArticleBrain sciences2021

Neurosensory Rehabilitation and Olfactory Network Recovery in Covid-19-related Olfactory Dysfunction.

Tom Wai-Hin Chung, Hui Zhang, Fergus Kai-Chuen Wong, Siddharth Sridhar, Kwok-Hung Chan, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Ivan Fan-Ngai Hung, Henry Ka-Fung Mak

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Tom Wai-Hin ChungDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0003-1780-821X
Hui ZhangDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Fergus Kai-Chuen WongDepartment of Ear, Nose and Throat Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China.ORCID 0000-0002-6620-2479
Siddharth SridharDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0002-2022-8307
Kwok-Hung ChanDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0003-1771-8249
Vincent Chi-Chung ChengDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Kwok-Yung YuenDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Ivan Fan-Ngai HungState Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China.
Henry Ka-Fung MakDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID 0000-0002-2007-0650
University of Hong Kong · HKPamela Youde Nethersole Eastern Hospital · CN

Funding

Consultancy Service for Enhancing Laboratory Surveillance of Emerging Infectious Diseases and Research Capability on Antimicrobial Resistance for the Department of Health of the Hong Kong Special Administrative Region Government N/AHigh Level-Hospital Program, Health Commission of Guangdong Province, China N/AHui Ming, Hui Hoy and Chow Sin Lan Charity Fund Limited N/AJessie & George Ho Charitable Foundation N/AMay Tam Mak Mei Yin N/AMichael Seak-Kan Tong N/APerfect Shape Medical Limited N/ARespiratory Viral Research Foundation N/ARichard Yu and Carol Yu N/ASanming Project of Medicine in Shenzhen SZSM201911014Shaw Foundation Hong Kong N/ATheme-Based Research Scheme of the Research Grants Council of the Hong Kong Special Administrative Region Government, China T11/707/15
6 · The paper itself

Abstract

Non-conductive olfactory dysfunction (OD) is an important extra-pulmonary manifestation of coronavirus disease 2019 (COVID-19). Olfactory bulb (OB) volume loss and olfactory network functional connectivity (FC) defects were identified in two patients suffering from prolonged COVID-19-related OD. One patient received olfactory treatment (OT) by the combination of oral vitamin A and smell training via the novel electronic portable aromatic rehabilitation (EPAR) diffusers. After four-weeks of OT, clinical recuperation of smell was correlated with interval increase of bilateral OB volumes [right: 22.5 mm

Indexed as

COVID-19olfactory dysfunctionresting-state fMRIsmell trainingvitamin A

Identifiers

PMID34071007
PMCPMC8224593
OpenAlexW3139282184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.