Evidence map›Paper›PMID 34070959›Full record

ArticleMolecules (Basel, Switzerland)2021

A Combined Experimental and Computational Study of Halogen and Hydrogen Bonding in Molecular Salts of 5-Bromocytosine.

Massimiliano Aschi, Giorgia Toto Brocchi, Gustavo Portalone

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Massimiliano AschiDipartimento di Scienze Fisiche e Chimiche, Università degli Studi di L'Aquila, Via Vetoio 10, 67100 Coppito, Italy.ORCID 0000-0003-2959-0158
Giorgia Toto BrocchiDipartimento di Chimica, Università di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Roma, Italy.
Gustavo PortaloneDipartimento di Chimica, Università di Roma "La Sapienza", Piazzale Aldo Moro 5, 00185 Roma, Italy.ORCID 0000-0001-5093-1207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although natural or artificial modified pyrimidine nucleobases represent important molecules with valuable properties as constituents of DNA and RNA, no systematic analyses of the structural aspects of bromo derivatives of cytosine have appeared so far in the literature. In view of the biochemical and pharmaceutical relevance of these compounds, six different crystals containing proton-transfer derivatives of 5-bromocytosine are prepared and analyzed in the solid-state by single crystal X-ray diffraction. All six compounds are organic salts, with proton transfer occurring to the N

Indexed as

Crystallography, X-RayCysteineCytosineDNAElectronsHalogensHydrogenHydrogen BondingModels, MolecularProtonsPyridinesRNAX-Ray Diffraction5-bromocytosineCysteineCytosineDNAHalogensHydrogenProtonspyridinePyridinesRNA5-bromocytosinebiomolecular engineeringDFTDNAhalogen bondinghydrogen bondingmodified nucleobasesmolecular recognitionQTAIMX-ray diffraction

Identifiers

PMID34070959
PMCPMC8196974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.