Evidence map›Paper›PMID 34070955›Full record

ArticleNutrients2021

Association between Geriatric Nutritional Risk Index and Post-Stroke Cognitive Outcomes.

Minwoo Lee, Jae-Sung Lim, Yerim Kim, Ju Hun Lee, Chul-Ho Kim, Sang-Hwa Lee, Min Uk Jang, Mi Sun Oh, Byung-Chul Lee, Kyung-Ho Yu

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  6. NutrigramFrontiers in nutrition · 2026
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  9. Observational
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  17. Geriatric Nutritional Risk Index is associated with adverse outcomes in patients with hypertension: the Fukushima Cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Minwoo LeeDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.ORCID 0000-0001-8474-5744
Jae-Sung LimDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Yerim KimDepartment of Neurology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul 05355, Korea.ORCID 0000-0002-7108-6302
Ju Hun LeeDepartment of Neurology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul 05355, Korea.
Chul-Ho KimDepartment of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chunchon 24253, Korea.ORCID 0000-0001-8762-8340
Sang-Hwa LeeDepartment of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chunchon 24253, Korea.ORCID 0000-0002-0609-1551
Min Uk JangDepartment of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong 18450, Korea.ORCID 0000-0001-8964-3288
Mi Sun OhDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Byung-Chul LeeDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Kyung-Ho YuDepartment of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Korea.
Hallym University · KRHallym University Sacred Heart Hospital · KRHallym University Dongtan Sacred Heart Hospital · KRUlsan College · KR

Funding

Institute for Information & Communications Technology Promotion 2018-0-00861
6 · The paper itself

Abstract

backgroundIt is not yet clear whether nutritional status is associated with post-stroke cognitive impairment (PSCI). We examined the geriatric nutritional risk index (GNRI) on the domain-specific cognitive outcomes 3 months after a stroke.

methodsA total of 344 patients with acute ischemic stroke were included for the analysis. The GNRI was calculated as 1.489 × serum albumin (g/L) + 41.7 × admission weight (kg)/ideal body weight (kg) and was dichotomized according to the prespecified cut-off points for no risk and any risks. The primary outcome was PSCI, defined as having adjusted z-scores of less than -2 standard deviations in at least one cognitive domain: executive/activation, memory, visuospatial and language. Multiple logistic regression and linear regression analyses were performed to investigate the association between the GNRI and cognitive outcomes.

resultsSeventy (20.3%) patients developed PSCI 3 months after a stroke. The mean GNRI was 106.1 ± 8.6, and 59 (17.2%) patients had low (<98) GNRI scores. A low GNRI was independently associated with the PSCI after adjusting for age, sex, education, initial stroke severity, stroke mechanism and left hemispheric lesion (odds ratio, 2.04; 95% confidence interval, 1.00-4.14). The GNRI scores were also significantly associated with the z-scores from the mini-mental status examination and the frontal domain (β = 0.04,

conclusionsA low GNRI was independently associated with the development of PSCI at 3 months after an ischemic stroke. The GNRI scores were specifically associated with the z-scores of the global cognition and frontal domain cognitive outcomes.

Indexed as

Nutritional StatusNutrition AssessmentAgedBody WeightCognitionCognitive DysfunctionFemaleGeriatric AssessmentHumansIschemic StrokeLogistic ModelsMaleMalnutritionMiddle AgedRetrospective StudiesRisk AssessmentSerum Albumincerebral infarctioncognitive impairmentgeriatric nutritional risk indexnutritionstroke

Identifiers

PMID34070955
PMCPMC8224551
OpenAlexW3163994647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.