Evidence map›Paper›PMID 34070936›Full record

ReviewJournal of fungi (Basel, Switzerland)2021

Potential of Anti-Cancer Activity of Secondary Metabolic Products from Marine Fungi.

Efaq Noman, Muhanna Mohammed Al-Shaibani, Muhammed Adnan Bakhrebah, Reyad Almoheer, Mohammed Al-Sahari, Adel Al-Gheethi, Radin Maya Saphira Radin Mohamed, Yaaser Qaeed Almulaiky, Wesam Hussain Abdulaal

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. UtilizingArchives of Razi Institute · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Marine-derived Compounds: A Powerful Platform for the Treatment of Alzheimer's Disease.Central nervous system agents in medicinal chemistry · 2024
    Review
  12. Article
  13. Bioprospecting ofFrontiers in microbiology · 2024
    Review
  14. Article
  15. Heliyon · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Efaq NomanDepartment of Applied Microbiology, Faculty of Applied Science, Taiz University, Taiz 00967, Yemen.ORCID 0000-0003-0612-5085
Muhanna Mohammed Al-ShaibaniMicro-pollutant Research Centre (MPRC), Faculty of Civil Engineering & Built Environment, Universiti Tun Hussein Onn Malaysia, Parit Raja, Batu Pahat, Johor 86400, Malaysia.ORCID 0000-0001-9925-4673
Muhammed Adnan BakhrebahLife Science and Environment Research Institute, King Abdulaziz City for Science and Technology (KACST), P.O. Box 6086, Riyadh 11442, Saudi Arabia.
Reyad AlmoheerSchool of Fundamental Science, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia.
Mohammed Al-SahariMicro-pollutant Research Centre (MPRC), Faculty of Civil Engineering & Built Environment, Universiti Tun Hussein Onn Malaysia, Parit Raja, Batu Pahat, Johor 86400, Malaysia.ORCID 0000-0001-7257-2954
Adel Al-GheethiMicro-pollutant Research Centre (MPRC), Faculty of Civil Engineering & Built Environment, Universiti Tun Hussein Onn Malaysia, Parit Raja, Batu Pahat, Johor 86400, Malaysia.ORCID 0000-0002-2023-9196
Radin Maya Saphira Radin MohamedMicro-pollutant Research Centre (MPRC), Faculty of Civil Engineering & Built Environment, Universiti Tun Hussein Onn Malaysia, Parit Raja, Batu Pahat, Johor 86400, Malaysia.
Yaaser Qaeed AlmulaikyDepartment of Chemistry, College of Science and Arts at Khulis, University of Jeddah, Jeddah 21921, Saudi Arabia.
Wesam Hussain AbdulaalCancer and Mutagenesis Unit, Department of Biochemistry, Faculty of Science,King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The promising feature of the fungi from the marine environment as a source for anticancer agents belongs to the fungal ability to produce several compounds and enzymes which contribute effectively against the cancer cells growth. L-asparaginase acts by degrading the asparagine which is the main substance of cancer cells. Moreover, the compounds produced during the secondary metabolic process acts by changing the cell morphology and DNA fragmentation leading to apoptosis of the cancer cells. The current review has analyed the available information on the anticancer activity of the fungi based on the data extracted from the Scopus database. The systematic and bibliometric analysis revealed many of the properties available for the fungi to be the best candidate as a source of anticancer drugs. Doxorubicin, actinomycin, and flavonoids are among the primary chemical drug used for cancer treatment. In comparison, the most anticancer compounds producing fungi are

Indexed as

anticancerfungiL-asparaginasemarineproduction

Identifiers

PMID34070936
PMCPMC8229146

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.