Evidence map›Paper›PMID 34070917›Full record

Trial reportNutrients2021

Regulation of Alcohol and Acetaldehyde Metabolism by a Mixture of

Su-Jin Jung, Ji-Hyun Hwang, Eun-Ock Park, Seung-Ok Lee, Yun-Jo Chung, Myung-Jun Chung, Sanghyun Lim, Tae-Joong Lim, Yunhi Ha, Byung-Hyun Park and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Effects of ParaprobioticJournal of microbiology and biotechnology · 2025
    Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. HostFrontiers in microbiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Observational
  17. Protection ofNutrients · 2023
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Su-Jin JungClinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Korea.
Ji-Hyun HwangClinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Korea.
Eun-Ock ParkClinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Korea.
Seung-Ok LeeBiomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Korea.
Yun-Jo ChungBiomedical Research Institute, Jeonbuk National University, Jeonju, Jeonbuk 54907, Korea.
Myung-Jun ChungR&D Center, Cell Biotech, Co., Ltd., Gimpo, Gyeongi 10003, Korea.
Sanghyun LimR&D Center, Cell Biotech, Co., Ltd., Gimpo, Gyeongi 10003, Korea.
Tae-Joong LimR&D Center, Cell Biotech, Co., Ltd., Gimpo, Gyeongi 10003, Korea.
Yunhi HaClinical Research and Development Team, Cell Biotech, Co., Ltd., Gimpo, Gyeongi 10003, Korea.ORCID 0000-0003-1449-5385
Byung-Hyun ParkDepartment of Biochemistry and Molecular Biology, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Korea.
Soo-Wan ChaeClinical Trial Center for Functional Foods, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Korea.
Jeonbuk National University Hospital · KRCell Biotech (South Korea) · KRJeonbuk National University · KR

Funding

This research was supported by funding from the Cell Biotech Co Ltd 2018-12
6 · The paper itself

Abstract

Excessive alcohol consumption is one of the most significant causes of morbidity and mortality worldwide. Alcohol is oxidized to toxic and carcinogenic acetaldehyde by alcohol dehydrogenase (ADH) and further oxidized to a non-toxic acetate by aldehyde dehydrogenase (ALDH). There are two major ALDH isoforms, cytosolic and mitochondrial, encoded by

Indexed as

AcetaldehydeAdultAlcohol DrinkingAldehyde Dehydrogenase, MitochondrialBifidobacteriumCross-Over StudiesDouble-Blind MethodEthanolHumansLactobacillusMaleProbioticsYoung AdultAcetaldehydeAldehyde Dehydrogenase, MitochondrialEthanolacetaldehydealcoholALDH2 geneBifidobacteriumLactobacillusprobiotics

Identifiers

PMID34070917
PMCPMC8228388
OpenAlexW3159214697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.