Evidence map›Paper›PMID 34070818›Full record

ArticleNutrients2021

Monosodium Glutamate Induces Changes in Hepatic and Renal Metabolic Profiles and Gut Microbiome of Wistar Rats.

Kanokwan Nahok, Jutarop Phetcharaburanin, Jia V Li, Atit Silsirivanit, Raynoo Thanan, Piyanard Boonnate, Jarus Joonhuathon, Amod Sharma, Sirirat Anutrakulchai, Carlo Selmi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. mSphere · 2026
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  9. Nutritional Criminology: Why the Emerging Research on Ultra-Processed Food Matters to Health and Justice.International journal of environmental research and public health · 2024
    Article
  10. Review
  11. Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and Planet.International journal of environmental research and public health · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Kanokwan NahokDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-0458-2816
Jutarop PhetcharaburaninDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-4727-8395
Jia V LiDepartment of Metabolism, Digestive Disease and Reproduction, Faculty of Medicine, Imperial College London, South Kensington, London SW7 2AZ, UK.ORCID 0000-0002-5763-6670
Atit SilsirivanitDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-5777-3843
Raynoo ThananDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-9001-1197
Piyanard BoonnateDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Jarus JoonhuathonNortheast Laboratory Animal Center, Khon Kaen University, Khon Kaen 40002, Thailand.
Amod SharmaChronic Kidney Disease Prevention in the Northeast Thailand (CKDNET), Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-2860-7790
Sirirat AnutrakulchaiChronic Kidney Disease Prevention in the Northeast Thailand (CKDNET), Khon Kaen University, Khon Kaen 40002, Thailand.
Carlo SelmiRheumatology and Clinical Immunology, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milan, Italy.
Ubon Cha'onDepartment of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-9909-8671
Khon Kaen University · THHumanitas University · ITImperial College London · GB

Funding

PKD1 SPLICING PATTERNS AND DISEASE PATHOGENESISK08DK002562 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI WATNICK, TERRY J · 1998 to 2002
$381k
Medical Research Council MR/P002536/1
6 · The paper itself

Abstract

The short- and long-term consumption of monosodium glutamate (MSG) increases urinary pH but the effects on the metabolic pathways in the liver, kidney and the gut microbiota remain unknown. To address this issue, we investigated adult male Wistar rats allocated to receive drinking water with or without 1 g% MSG for 2 weeks (

Indexed as

AnimalsDisease Models, AnimalFlavoring AgentsGastrointestinal MicrobiomeKidneyLiverMaleModels, AnimalRatsRats, WistarSodium GlutamateFlavoring AgentsSodium Glutamategut microbiotametabolic pathwaymetabolomicsmicrobiomemonosodium glutamatetrimethylamine

Identifiers

PMID34070818
PMCPMC8229789
OpenAlexW3165160492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.