Evidence map›Paper›PMID 34070808›Full record

ArticleInternational journal of molecular sciences2021

The Density of Group I mGlu

Alejandro Martín-Belmonte, Carolina Aguado, Rocío Alfaro-Ruiz, José Luis Albasanz, Mairena Martín, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Luján

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Alejandro Martín-BelmonteSynaptic Structure Laboratory, Instituto de Investigación en Discapacidades Neurológicas (IDINE), Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Campus Biosanitario, C/Almansa 14, 02006 Albacete, Spain.ORCID 0000-0001-5006-2523
Carolina AguadoSynaptic Structure Laboratory, Instituto de Investigación en Discapacidades Neurológicas (IDINE), Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Campus Biosanitario, C/Almansa 14, 02006 Albacete, Spain.
Rocío Alfaro-RuizSynaptic Structure Laboratory, Instituto de Investigación en Discapacidades Neurológicas (IDINE), Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Campus Biosanitario, C/Almansa 14, 02006 Albacete, Spain.
José Luis AlbasanzDepartment of Inorganic, Organic and Biochemistry, Faculty of Chemical and Technological Sciences, Universidad de Castilla-La Mancha, School of Medicine of Ciudad Real, Regional Center of Biomedical Research (CRIB), 13071 Ciudad Real, Spain.ORCID 0000-0002-9927-5076
Mairena MartínDepartment of Inorganic, Organic and Biochemistry, Faculty of Chemical and Technological Sciences, Universidad de Castilla-La Mancha, School of Medicine of Ciudad Real, Regional Center of Biomedical Research (CRIB), 13071 Ciudad Real, Spain.
Ana Esther Moreno-MartínezSynaptic Structure Laboratory, Instituto de Investigación en Discapacidades Neurológicas (IDINE), Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Campus Biosanitario, C/Almansa 14, 02006 Albacete, Spain.
Yugo FukazawaDivision of Brain Structure and Function, Research Center for Child Mental Development, Life Science Innovation Center, School of Medical Science, University of Fukui, Fukui 910-1193, Japan.
Rafael LujánSynaptic Structure Laboratory, Instituto de Investigación en Discapacidades Neurológicas (IDINE), Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Campus Biosanitario, C/Almansa 14, 02006 Albacete, Spain.ORCID 0000-0003-2001-9545
University of Castilla-La Mancha · ESUniversity of Fukui · JP

Funding

Junta de Comunidades de Castilla-La Mancha SBPLY/17/180501/000229Junta de Comunidades de Castilla-La Mancha SBPLY/19/180501/000251Ministerio de Ciencia y Tecnología PID2019-109206GB-I00Ministerio de Ciencia y Tecnología RTI2018-095812-B-I00University of Fukui 19K22469University of Fukui 20H05058
6 · The paper itself

Abstract

Metabotropic glutamate receptor subtype 5 (mGlu

Indexed as

Alzheimer DiseaseAmyloid beta-Protein PrecursorAnimalsCell MembraneDisease Models, AnimalGene Expression RegulationGTP-Binding Protein alpha Subunits, Gq-G11HippocampusHumansMaleMiceMice, TransgenicPhospholipase C betaPresenilin-1Pyramidal CellsReceptor, Metabotropic Glutamate 5Amyloid beta-Protein PrecursorAPP protein, mouseGTP-Binding Protein alpha Subunits, Gq-G11Phospholipase C betaPresenilin-1Receptor, Metabotropic Glutamate 5AD mouse modelAlzheimer’s diseaseelectron microscopyfreeze-fracturehippocampusimmunohistochemistrymGlu receptors

Identifiers

PMID34070808
PMCPMC8199018
OpenAlexW3164277861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.