Evidence map›Paper›PMID 34070768›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Effects of Anti-Inflammatory Treatment and Surgical Intervention on Endothelial Glycocalyx, Peripheral and Coronary Microcirculatory Function and Myocardial Deformation in Inflammatory Bowel Disease Patients: A Two-Arms Two-Stage Clinical Trial.

Charilaos Triantafyllou, Maria Nikolaou, Ignatios Ikonomidis, Giorgos Bamias, Dimitrios Kouretas, Ioanna Andreadou, Maria Tsoumani, John Thymis, Ioannis Papaconstantinou

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Charilaos Triantafyllou2nd Academic Department of Cardiology, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Maria NikolaouDepartment of Cardiology, Amalia Fleming General Hospital of Athens, 15127 Athens, Greece.
Ignatios Ikonomidis2nd Academic Department of Cardiology, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0001-8241-7886
Giorgos BamiasGI-Unit, 3rd Academic Department of Internal Medicine, Sotiria Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-5492-5717
Dimitrios KouretasDepartment of Biochemistry and Biotechnology, University of Thessaly, 41500 Larissa, Greece.
Ioanna AndreadouLaboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, 15741 Athens, Greece.
Maria TsoumaniLaboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, 15741 Athens, Greece.
John Thymis2nd Academic Department of Cardiology, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Ioannis Papaconstantinou2nd Academic Department of Surgery, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
National and Kapodistrian University of Athens · GRSimanogleio-Amalia Fleming General Hospital · GRUniversity of Thessaly · GR

Funding

HELLENIC SOCIETY OF IBD STUDY (EOMIFNE) protocol code 2017EOMIFNEp1
6 · The paper itself

Abstract

Sixty inflammatory bowel disease (IBD) patients (45 Crohn disease and 15 ulcerative colitis, 40 ± 13 years, 53% male) were examined at baseline and 4 months after intervention (surgical (35 patients) or anti-TNFa treatment (25 patients)). IBD severity, using Mayo score, Harvey-Bradshaw Index (HBI) and biomarkers, was correlated with cardiovascular markers. At baseline, the disease severity, the white blood cells (WBC) values and the reducing power (RP) were significantly correlated with the aortic pulse wave velocity (PWV) (

Indexed as

arterial stiffnessatherosclerosisCrohn’s diseaseendothelial dysfunctionendothelial glycocalyxinflammationinflammatory bowel diseaseoxidative stressulcerative colitis

Identifiers

PMID34070768
PMCPMC8227308
OpenAlexW3165234881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.