ArticlePharmaceutics2021
The Novel Use of PVP K30 as Templating Agent in Production of Porous Lactose.
Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Preparation and Application of Shen Ling Cao Composite Particles with Different Structures Based on Co-Spray Drying.Pharmaceuticals (Basel, Switzerland) · 2025Article
- The Comparison between Pilot-Grade Spray Dryer and Laboratory-Grade Spray Dryer: Structure, Powder Properties and Application for Direct Compaction.AAPS PharmSciTech · 2024Article
- Establishment and Validation of a Transdermal Drug Delivery System for the Anti-Depressant Drug Citalopram Hydrobromide.Molecules (Basel, Switzerland) · 2024Article
- The Fabrication, Drug Loading, and Release Behavior of Porous Mannitol.Molecules (Basel, Switzerland) · 2024Article
- Article
- Fabrication and Characterization of β-Cyclodextrin/Molecules (Basel, Switzerland) · 2022Article
- Surface Modifiers on Composite Particles for Direct Compaction.Pharmaceutics · 2022Review
- Evaluation of Hydrophilic and Hydrophobic Silica Particles on the Release Kinetics of Essential Oil Pickering Emulsions.ACS omega · 2022Article
- Preparation and Evaluation of Silymarin-Loaded Solid Eutectic for Enhanced Anti-Inflammatory, Hepatoprotective Effect:Oxidative medicine and cellular longevity · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is necessary to prepare porous lactose in order to improve the dissolution behavior of insoluble active ingredient. In this study, polyvinylpyrrolidone K30 (PVP K30) was firstly utilized as a templating agent with different use levels in preparing porous lactose. Then, the physical properties were profoundly characterized. Finally, the porous lactose was also employed as a health functional food/drug carrier to explore the effect on the dissolution behavior of curcumin. The results confirmed that (i) porous lactose was successfully prepared using PVP K30 as templating agent; (ii) PVP K30 significantly improved the yield of lactose in the spray drying; (iii) the improved powder properties of porous lactose were more conducive to the downstream operating process for the preparation of health functional food or drug; and (iv) the porous lactose significantly improved the dissolution behavior of curcumin. Therefore, the results obtained are beneficial to boosting the development of porous materials.
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