Evidence map›Paper›PMID 34070691›Full record

ArticleInternational journal of molecular sciences2021

A Matrix Metalloproteinase Mediates Tracheal Development in

Yi Wei, Xiao-Lin Zhou, Tai-Hang Liu, Peng Chen, Xia Jiang, Zhan-Qi Dong, Min-Hui Pan, Cheng Lu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yi WeiState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Xiao-Lin ZhouState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Tai-Hang LiuState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Peng ChenState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Xia JiangState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Zhan-Qi DongState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Min-Hui PanState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
Cheng LuState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China.
State Key Laboratory of Silkworm Genomic BiologySouthwest University · CN

Funding

National Natural Science Foundation of China Nos. 31872427National Natural Science Foundation of China Nos. 31872428Natural Science Foundation of Chongqing cstc2018jcyjAX0528Natural Science Foundation of Chongqing cstc2020jscx-msxmX0045The Municipal Graduate Student Research Innovation Project of Chongqing No. CYB20116
6 · The paper itself

Abstract

The trachea of insects is a tubular epithelia tissue that transports oxygen and other gases. It serves as a useful model for the studying of the cellular and molecular events involved in epithelial tube formation. Almost all of the extracellular matrix can be degraded by Matrix metalloproteinases (MMPs), which is closely related to the processes of development and regeneration. The regulation of trachea by MMPs is roughly known in previous studies, but the detailed regulation mechanism and involved gene function are not fully explored. In this article, we found MMP1 expressed highly during tracheal remodeling, and knocked out it makes the tracheal branch number reduced in

Indexed as

BombyxInsect ProteinsMatrix Metalloproteinase 1OrganogenesisAnimalsTracheaInsect ProteinsMatrix Metalloproteinase 1Bombyx moriextracellular matrixmatrix metalloproteinasestrachea

Identifiers

PMID34070691
PMCPMC8198827
OpenAlexW3165130982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.