Evidence map›Paper›PMID 34070690›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Dielectric Imaging of Fixed HeLa Cells by In-Liquid Scanning Dielectric Force Volume Microscopy.

Martí Checa, Ruben Millan-Solsona, Adrianna Glinkowska Mares, Silvia Pujals, Gabriel Gomila

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Martí ChecaNanoscale Bioelectric Characterization, Institut de Bioenginyeria de Catalunya (IBEC), The Barcelona Institute of Science and Technology (BIST), c/Baldiri I Reixac 11-15, 08028 Barcelona, Spain.ORCID 0000-0003-2607-6866
Ruben Millan-SolsonaNanoscale Bioelectric Characterization, Institut de Bioenginyeria de Catalunya (IBEC), The Barcelona Institute of Science and Technology (BIST), c/Baldiri I Reixac 11-15, 08028 Barcelona, Spain.ORCID 0000-0003-0912-7246
Adrianna Glinkowska MaresNanoscopy for Nanomedicine, Institut de Bioenginyeria de Catalunya (IBEC), The Barcelona Institute of Science and Technology (BIST), c/Baldiri I Reixac 11-15, 08028 Barcelona, Spain.ORCID 0000-0002-1560-3918
Silvia PujalsDepartament d'Enginyeria Electrònica i Biomèdica, Universitat de Barcelona, c/Martí i Franquès 1, 08028 Barcelona, Spain.ORCID 0000-0003-1776-4296
Gabriel GomilaNanoscale Bioelectric Characterization, Institut de Bioenginyeria de Catalunya (IBEC), The Barcelona Institute of Science and Technology (BIST), c/Baldiri I Reixac 11-15, 08028 Barcelona, Spain.ORCID 0000-0002-1949-1757
Institute for Bioengineering of Catalonia · ES

Funding

Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona LCF/BQ/DI17/11620054Generalitat de Catalunya 2017-SGR1079H2020 Marie Skłodowska-Curie Actions 713673Ministerio de Economía, Industria y Competitividad, Gobierno de España PID2019-111376RA-I00
6 · The paper itself

Abstract

Mapping the dielectric properties of cells with nanoscale spatial resolution can be an important tool in nanomedicine and nanotoxicity analysis, which can complement structural and mechanical nanoscale measurements. Recently we have shown that dielectric constant maps can be obtained on dried fixed cells in air environment by means of scanning dielectric force volume microscopy. Here, we demonstrate that such measurements can also be performed in the much more challenging case of fixed cells in liquid environment. Performing the measurements in liquid media contributes to preserve better the structure of the fixed cells, while also enabling accessing the local dielectric properties under fully hydrated conditions. The results shown in this work pave the way to address the nanoscale dielectric imaging of living cells, for which still further developments are required, as discussed here.

Indexed as

atomic force microscopy (AFM)dielectric propertieselectrostatic force microscopy (EFM)functional microscopyscanning dielectric microscopy (SDM)scanning probe microscopy (SPM)

Identifiers

PMID34070690
PMCPMC8226567
OpenAlexW3164276625

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.