Evidence map›Paper›PMID 34070674›Full record

ReviewInternational journal of molecular sciences2021

Breast Cancer Predisposition Genes and Synthetic Lethality.

Hannah E Neiger, Emily L Siegler, Yihui Shi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Neddylation as a target in PIK3CA-mutated head and neck cancer.Biochemical and biophysical research communications · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
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  19. PARP Inhibition and Beyond in BRCA-Associated Breast Cancer in Women: A State-Of-The-Art Summary of Preclinical Research on Risk Reduction and Clinical Benefits.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hannah E NeigerCollege of Graduate Studies, California Northstate University, Elk Grove, CA 95757, USA.
Emily L SieglerCollege of Medicine, California Northstate University, Elk Grove, CA 95757, USA.
Yihui ShiCollege of Medicine, California Northstate University, Elk Grove, CA 95757, USA.ORCID 0000-0002-8014-1457

Funding

Identification of Synthetic Lethal Partners of Cancer Germline Mutations using PanCancer Human Primary Tumor DataR21CA231111 · NCI · SRI INTERNATIONAL · PI SHI, YIHUI · 2019 to 2020
$385k
NIH/NCI R21CA231111
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseSynthetic Lethal MutationsBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsDNA RepairFanconi Anemia Complementation Group N ProteinFemaleHumansBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanFanconi Anemia Complementation Group N ProteinPALB2 protein, humanBRCA1/BRCA2CPGsDNA repairhereditary breast cancerPARPisynthetic lethality

Identifiers

PMID34070674
PMCPMC8198377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.