Evidence map›Paper›PMID 34070646›Full record

ReviewPharmaceutics2021

Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals.

Mizraín Solares-Briones, Guadalupe Coyote-Dotor, José C Páez-Franco, Miriam R Zermeño-Ortega, Carmen Myriam de la O Contreras, Daniel Canseco-González, Alcives Avila-Sorrosa, David Morales-Morales, Juan M Germán-Acacio

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  17. Exploring LIPIDs for their potential to improves bioavailability of lipophilic drugs candidates: A review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mizraín Solares-BrionesRed de Apoyo a la Investigación, Coordinación de la Investigación Científica-UNAM, Instituto Nacional de Ciencias Médicas y Nutrición SZ, Ciudad de México CP 14000, Mexico.
Guadalupe Coyote-DotorRed de Apoyo a la Investigación, Coordinación de la Investigación Científica-UNAM, Instituto Nacional de Ciencias Médicas y Nutrición SZ, Ciudad de México CP 14000, Mexico.
José C Páez-FrancoRed de Apoyo a la Investigación, Coordinación de la Investigación Científica-UNAM, Instituto Nacional de Ciencias Médicas y Nutrición SZ, Ciudad de México CP 14000, Mexico.
Miriam R Zermeño-OrtegaFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario No. 1, Nuevo Campus Universitario, Apdo. Postal 1552, Chihuahua CP 31125, Mexico.
Carmen Myriam de la O ContrerasFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario No. 1, Nuevo Campus Universitario, Apdo. Postal 1552, Chihuahua CP 31125, Mexico.
Daniel Canseco-GonzálezCONACYT-Laboratorio Nacional de Investigación y Servicio Agroalimentario y Forestal, Universidad Autónoma de Chapingo, Texcoco de Mora CP 56230, Mexico.
Alcives Avila-SorrosaInstituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Departamento de Química Orgánica, Carpio y Plan de Ayala S/N, Colonia Santo Tomás, Ciudad de México CP 11340, Mexico.ORCID 0000-0001-7764-6676
David Morales-MoralesInstituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Ciudad de México CP 04510, Mexico.ORCID 0000-0002-7984-1819
Juan M Germán-AcacioRed de Apoyo a la Investigación, Coordinación de la Investigación Científica-UNAM, Instituto Nacional de Ciencias Médicas y Nutrición SZ, Ciudad de México CP 14000, Mexico.ORCID 0000-0002-5915-2944

Funding

Consejo Nacional de Ciencia y Tecnologia. Mexico A1-S-33933Consejo Nacional de Ciencia y Tecnologia. Mexico FOINS 307152Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México PAPIIT IN210520Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México PAPIIT IT200920
6 · The paper itself

Abstract

Mechanochemistry is considered an alternative attractive greener approach to prepare diverse molecular compounds and has become an important synthetic tool in different fields (e.g., physics, chemistry, and material science) since is considered an ecofriendly procedure that can be carried out under solvent free conditions or in the presence of minimal quantities of solvent (catalytic amounts). Being able to substitute, in many cases, classical solution reactions often requiring significant amounts of solvents. These sustainable methods have had an enormous impact on a great variety of chemistry fields, including catalysis, organic synthesis, metal complexes formation, preparation of multicomponent pharmaceutical solid forms, etc. In this sense, we are interested in highlighting the advantages of mechanochemical methods on the obtaining of pharmaceutical cocrystals. Hence, in this review, we describe and discuss the relevance of mechanochemical procedures in the formation of multicomponent solid forms focusing on pharmaceutical cocrystals. Additionally, at the end of this paper, we collect a chronological survey of the most representative scientific papers reporting the mechanochemical synthesis of cocrystals.

Indexed as

green reactionsmechanochemistrypharmaceutical cocrystals

Identifiers

PMID34070646
PMCPMC8228148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.