Evidence map›Paper›PMID 34070642›Full record

ArticleInternational journal of molecular sciences2021

Molecular Elucidation of a Urate Oxidase from

Yi-Chih Chiu, Ting-Syuan Hsu, Chen-Yu Huang, Chun-Hua Hsu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Enzymes and Enzyme Inhibitors-Applications in Medicine and Diagnosis.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yi-Chih ChiuGenome and Systems Biology Degree Program, National Taiwan University and Academia Sinica, Taipei 115024, Taiwan.
Ting-Syuan HsuTaipei First Girl High School, Taipei 10045, Taiwan.
Chen-Yu HuangTaipei First Girl High School, Taipei 10045, Taiwan.
Chun-Hua HsuGenome and Systems Biology Degree Program, National Taiwan University and Academia Sinica, Taipei 115024, Taiwan.ORCID 0000-0002-0008-7383
National Taiwan University · TW

Funding

Ministry of Science and Technology, Taiwan MOST 108-2113-M-002-011Ministry of Science and Technology, Taiwan MOST 108-2628-B-002-013Ministry of Science and Technology, Taiwan MOST 109-2113-M-002-003Ministry of Science and Technology, Taiwan MOST 109-2628-B-002-037National Taiwan University, Taiwan NTU-CDP-106R7867National Taiwan University, Taiwan NTU-CDP-108L7861
6 · The paper itself

Abstract

Urate oxidase initiates the uric acid degradation pathways and is extensively used for protein drug development for gout therapy and serum uric acid diagnosis. We first present the biochemical and structural elucidation of a urate oxidase from the extremophile microorganism

Indexed as

Bacterial ProteinsDeinococcusUrate OxidaseAnimalsGoutHumansHyperuricemiaRecombinant ProteinsBacterial ProteinsRecombinant ProteinsUrate OxidaseDeinococcus radioduransgout therapyuricase

Identifiers

PMID34070642
PMCPMC8199477
OpenAlexW3165579266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.