Evidence map›Paper›PMID 34070636›Full record

ReviewInternational journal of molecular sciences2021

Ionic Liquids-A Review of Their Toxicity to Living Organisms.

Ana R P Gonçalves, Xavier Paredes, A F Cristino, F J V Santos, Carla S G P Queirós

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

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  17. On the Solvation Properties of Menthol-Thymol Mixtures. A Molecular Dynamics Investigation.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana R P GonçalvesCentro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.
Xavier ParedesCentro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.ORCID 0000-0002-2322-8425
A F CristinoCentro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.ORCID 0000-0002-9867-1894
F J V SantosCentro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.ORCID 0000-0002-4555-8273
Carla S G P QueirósCentro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionic liquids (ILs) were initially hailed as a green alternative to traditional solvents because of their almost non-existent vapor pressure as ecological replacement of most common volatile solvents in industrial processes for their damaging effects on the environment. It is common knowledge that they are not as green as desired, and more thought must be put into the biological consequences of their industrial use. Still, compared to the amount of research studying their physicochemical properties and potential applications in different areas, there is a scarcity of scientific papers regarding how these substances interact with different organisms. The intent of this review was to compile the information published in this area since 2015 to allow the reader to better understand how, for example, bacteria, plants, fish, etc., react to the presence of this family of liquids. In general, lipophilicity is one of the main drivers of toxicity and thus the type of cation. The anion tends to play a minor (but not negligible) role, but more research is needed since, owing to the very nature of ILs, except for the most common ones (imidazolium and ammonium-based), many of them are subject to only one or two articles.

Indexed as

AnimalsHumansIonic LiquidsPlantsIonic Liquidsantimicrobial activityecotoxicityIonic liquidstoxicity

Identifiers

PMID34070636
PMCPMC8198260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.