Evidence map›Paper›PMID 34070622›Full record

ArticleCells2021

Effects of FGFR Tyrosine Kinase Inhibition in OLN-93 Oligodendrocytes.

Ranjithkumar Rajendran, Gregor Böttiger, Niklas Dentzien, Vinothkumar Rajendran, Bischand Sharifi, Süleyman Ergün, Christine Stadelmann, Srikanth Karnati, Martin Berghoff

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Oligodendrocyte-Specific Deletion ofInternational journal of molecular sciences · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ranjithkumar RajendranExperimental Neurology, Department of Neurology, Justus Liebig University of Giessen, 35385 Giessen, Germany.
Gregor BöttigerExperimental Neurology, Department of Neurology, Justus Liebig University of Giessen, 35385 Giessen, Germany.ORCID 0000-0002-2557-3302
Niklas DentzienExperimental Neurology, Department of Neurology, Justus Liebig University of Giessen, 35385 Giessen, Germany.ORCID 0000-0002-6354-3972
Vinothkumar RajendranExperimental Neurology, Department of Neurology, Justus Liebig University of Giessen, 35385 Giessen, Germany.
Bischand SharifiExperimental Neurology, Department of Neurology, Justus Liebig University of Giessen, 35385 Giessen, Germany.
Süleyman ErgünInstitute of Anatomy and Cell Biology, University of Würzburg, Koellikerstrasse 6, 97080 Würzburg, Germany.
Christine StadelmannInstitute for Neuropathology, Clinic for Neurology, University Medical Center, 37075 Göttingen, Germany.
Srikanth KarnatiInstitute of Anatomy and Cell Biology, University of Würzburg, Koellikerstrasse 6, 97080 Würzburg, Germany.ORCID 0000-0001-9083-2916
Martin BerghoffExperimental Neurology, Department of Neurology, Justus Liebig University of Giessen, 35385 Giessen, Germany.
Justus-Liebig-Universität Gießen · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor (FGF) signaling is involved in the pathogenesis of multiple sclerosis (MS). Data from neuropathology studies suggest that FGF signaling contributes to the failure of remyelination in MS. In MOG

Indexed as

AnimalsBenzamidesBenzimidazolesCell LineMultiple SclerosisOligodendrogliaPiperazinesProtein Kinase InhibitorsPyrazolesQuinolonesRatsReceptor, Fibroblast Growth Factor, Type 1Remyelination4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-oneAZD4547BenzamidesBenzimidazolesFGFR1 protein, humanPiperazinesProtein Kinase InhibitorsPyrazolesQuinolonesReceptor, Fibroblast Growth Factor, Type 1AZD4547dovitinibFGFR signalingmultiple sclerosismyelinoligodendrocytes

Identifiers

PMID34070622
PMCPMC8228431
OpenAlexW3164324281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.