Evidence map›Paper›PMID 34070597›Full record

ArticleInternational journal of molecular sciences2021

Polymorphisms in

Dorota Butkiewicz, Małgorzata Krześniak, Agnieszka Gdowicz-Kłosok, Monika Giglok, Małgorzata Marszałek-Zeńczak, Rafał Suwiński

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Meta-analysis ofInternational journal of immunopathology and pharmacology
    Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dorota ButkiewiczCenter for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.ORCID 0000-0002-4043-3789
Małgorzata KrześniakCenter for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Agnieszka Gdowicz-KłosokCenter for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Monika GiglokII Radiotherapy and Chemotherapy Clinic and Teaching Hospital, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Małgorzata Marszałek-ZeńczakDepartment of Molecular and Systems Biology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznań, Poland.ORCID 0000-0003-3498-3159
Rafał SuwińskiII Radiotherapy and Chemotherapy Clinic and Teaching Hospital, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.ORCID 0000-0002-3895-7938
The Maria Sklodowska-Curie National Research Institute of Oncology · PLInstitute of Bioorganic Chemistry, Polish Academy of Sciences · PL

Funding

National Science Centre (NCN), Poland 2012/05/B/NZ5/01905
6 · The paper itself

Abstract

For non-small cell lung cancer (NSCLC), radiotherapy (RT) and platinum-based chemotherapy (CHT) are among the main treatment options. On the other hand, radioresistance and cytotoxic drug resistance are common causes of failure. The epidermal growth factor receptor (EGFR) plays an important role in radioresponse and therapy resistance. We hypothesized that single nucleotide polymorphisms (SNPs) in the

Indexed as

Carcinoma, Non-Small-Cell LungChemoradiotherapyLung NeoplasmsPolymorphism, Single NucleotideAgedDisease-Free SurvivalErbB ReceptorsFemaleHumansMaleMiddle AgedNeoplasm ProteinsPlatinumSurvival RateEGFR protein, humanErbB ReceptorsNeoplasm ProteinsPlatinumEGFRlung cancerpolymorphismprognosisradioresponseradiotherapyrecurrencetherapy outcome

Identifiers

PMID34070597
PMCPMC8197839
OpenAlexW3164408489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.