Evidence map›Paper›PMID 34070571›Full record

ArticleBrain sciences2021

Of Criteria and Men-Diagnosing Atypical Parkinsonism: Towards an Algorithmic Approach.

Liviu Cozma, Mioara Avasilichioaei, Natalia Dima, Bogdan Ovidiu Popescu

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical Spectrum of Tauopathies.Frontiers in neurology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liviu CozmaDepartment of Clinical Neurosciences, School of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Mioara AvasilichioaeiDepartment of Clinical Neurosciences, School of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Natalia DimaDepartment of Clinical Neurosciences, School of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Bogdan Ovidiu PopescuDepartment of Clinical Neurosciences, School of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-4826-2598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosing atypical parkinsonism can be an error-exposed undertaking in the context of elaborate criteria coupled with time restraints on their comprehensive application. We conducted a retrospective, descriptive study of diagnostic accuracy among physicians at two tertiary neurology centers in Romania and developed an algorithmic tool for comparison purposes. As many as 90 patients qualified for inclusion in the study, with 77 patients actually complying with atypical parkinsonism criteria. Overall, physician-established diagnoses may be incorrect in about one-fourth of cases. The reasons for this finding span a wide range of possibilities, from terminology-related inaccuracies to criteria sophistication. A Boolean-logic algorithmic approach to diagnosis might decrease misdiagnosis rates. These findings prepare the ground for the future refinement of an algorithmic application to be fully validated in a prospective study for the benefit of patients and health professionals alike.

Indexed as

atypical parkinsonismCBDcorticobasal degenerationdementia with Lewy bodiesdiagnostic algorithmDLBMSAmultiple system atrophyprogressive supranuclear palsyPSP

Identifiers

PMID34070571
PMCPMC8230204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.