Evidence map›Paper›PMID 34070537›Full record

ReviewMolecules (Basel, Switzerland)2021

Radiotracers for Bone Marrow Infection Imaging.

Lars Jødal, Pia Afzelius, Aage Kristian Olsen Alstrup, Svend Borup Jensen

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. BMC oral health · 2026
    Article
  2. Article
  3. Biodistribution and dosimetry ofMedical physics · 2025
    Article
  4. Metabolic Differences in Neuroimaging with [Tomography (Ann Arbor, Mich.) · 2025
    Article
  5. Radiosynthesis and Preclinical Evaluation of [Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lars JødalDepartment of Nuclear Medicine, Aalborg University Hospital, DK-9000 Aalborg, Denmark.ORCID 0000-0002-6811-0172
Pia AfzeliusZealand Hospital, Køge, Copenhagen University Hospital, DK-4600 Køge, Denmark.ORCID 0000-0003-1512-4981
Aage Kristian Olsen AlstrupDepartment of Nuclear Medicine & PET, Aarhus University Hospital, DK-8200 Aarhus, Denmark.ORCID 0000-0002-0084-9122
Svend Borup JensenDepartment of Nuclear Medicine, Aalborg University Hospital, DK-9000 Aalborg, Denmark.ORCID 0000-0001-8575-3703
Aalborg University Hospital · DKAarhus University · DKCopenhagen University Hospital · DK

Funding

Teknologi og Produktion, Det Frie Forskningsråd 0602-01911B (11-107077)
6 · The paper itself

Abstract

introductionRadiotracers are widely used in medical imaging, using techniques of gamma-camera imaging (scintigraphy and SPECT) or positron emission tomography (PET). In bone marrow infection, there is no single routine test available that can detect infection with sufficiently high diagnostic accuracy. Here, we review radiotracers used for imaging of bone marrow infection, also known as osteomyelitis, with a focus on why these molecules are relevant for the task, based on their physiological uptake mechanisms. The review comprises [

conclusionMolecular radiotracers allow studies of physiological processes such as infection. None of the reviewed molecules are ideal for the imaging of infections, whether bone marrow or otherwise, but each can give information about a separate aspect such as physiology or biochemistry. Knowledge of uptake mechanisms, pitfalls, and challenges is useful in both the use and development of medically relevant radioactive tracers.

Indexed as

Bone MarrowHumansPositron-Emission TomographyRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonRadiopharmaceuticalsFDGFDSGa-citrateIL-8methionineosteomyelitisPETradionuclidesSiglec-9SPECTUBIubiquicidin

Identifiers

PMID34070537
PMCPMC8198735
OpenAlexW3165294208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.