ReviewJournal of cardiovascular development and disease2021
Patent Foramen Ovale-A Not So Innocuous Septal Atrial Defect in Adults.
Review in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 12 citations in OpenAlex.
- The relationship between anxiety and patent foramen ovale: a preliminary study.BMC psychology · 2026Observational
- Article
- Catheter-Based Valvular and Structural Interventions in Cancer Patients.Current cardiology reports · 2026Review
- Mechanical thrombectomy for massive PE with incidental discovery of a patent foramen ovale: a case report.CVIR endovascular · 2026Article
- Article
- Serotonin as a potential marker of endothelial dysfunction for cerebral embolism in patients with persistent foramen ovale.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- The Congenital Malformation of the Interatrial Septum-A Review of Its Development and Embryology with Clinical Implications.Journal of developmental biology · 2025Review
- Diffusion tensor image analysis along the perivascular space index and visual analogue scales in female patients with patent foramen ovale and migraine perform better after percutaneous closure.Quantitative imaging in medicine and surgery · 2025Article
- The Unique Case of Acute Limb Ischemia in a Patient With a Patent Foramen Ovale.Vascular and endovascular surgery · 2024Review
- Arteria lusoria with patent foramen ovale: clinical and embryological significance with literature review.Surgical and radiologic anatomy : SRA · 2023Review
- Disappearance of aura symptoms in patients with hemiplegic migraine after patent foramen ovale closure: a case report and literature review.Frontiers in neurology · 2023Article
- Case report: Anxiety and depression as initial symptoms in a patient with acute hypoxia and patent foramen ovale.Frontiers in psychiatry · 2023Article
- Synchronous multimode ultrasound for assessing right-to-left shunt: a prospective clinical study.Frontiers in neurology · 2023Article
- The Patent Foramen Ovale and Migraine: Associated Mechanisms and Perspectives from MRI Evidence.Brain sciences · 2022Review
- Patent foramen ovale with cryptogenic stroke: A case report.Medicine internationalArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patent foramen ovale (PFO) is a common congenital atrial septal defect with an incidence of 15-35% in the adult population. The development of the interatrial septum is a process that begins in the fourth gestational week and is completed only after birth. During intrauterine life, the foramen ovale allows the passage of highly oxygenated blood from the right to the left atrium and into the systemic arteries, thus bypassing the pulmonary circulation. In 75% of the general population, the foramen ovale closes after birth, and only an oval depression, called fossa ovalis, remains on the right side of the interatrial septum. Patent foramen ovale can be associated with various clinically important conditions, including migraine and stroke, or decompression illness in divers. The aim of this review is to summarize the PFO developmental and anatomical features and to discuss the clinical risks associated with this atrial septal defect in adults.
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